The power of genetic diversity in genome-wide association studies of lipids.
Link: https://doi.org/10.1038/s41586-021-04064-3
Authors: Graham, Sarah E; Clarke, Shoa L; Wu, Kuan-Han H; Kanoni, Stavroula; Zajac, Greg J M; Ramdas, Shweta; Surakka, Ida; Ntalla, Ioanna; Vedantam, Sailaja; Winkler, Thomas W; Locke, Adam E; Marouli, Eirini; Hwang, Mi Yeong; Han, Sohee; Narita, Akira; Choudhury, Ananyo; Bentley, Amy R; Ekoru, Kenneth; Verma, Anurag; Trivedi, Bhavi; Martin, Hilary C; Hunt, Karen A; Hui, Qin; Klarin, Derek; Zhu, Xiang; Thorleifsson, Gudmar; Helgadottir, Anna; Gudbjartsson, Daniel F; Holm, Hilma; Olafsson, Isleifur; Akiyama, Masato; Sakaue, Saori; Terao, Chikashi; Kanai, Masahiro; Zhou, Wei; Brumpton, Ben M; Rasheed, Humaira; Ruotsalainen, Sanni E; Havulinna, Aki S; Veturi, Yogasudha; Feng, QiPing; Rosenthal, Elisabeth A; Lingren, Todd; Pacheco, Jennifer Allen; Pendergrass, Sarah A; Haessler, Jeffrey; Giulianini, Franco; Bradford, Yuki; Miller, Jason E; Campbell, Archie; Lin, Kuang; Millwood, Iona Y; Hindy, George; Rasheed, Asif; Faul, Jessica D; Zhao, Wei; Weir, David R; Turman, Constance; Huang, Hongyan; Graff, Mariaelisa; Mahajan, Anubha; Brown, Michael R; Zhang, Weihua; Yu, Ketian; Schmidt, Ellen M; Pandit, Anita; Gustafsson, Stefan; Yin, Xianyong; Luan, Jian’an; Zhao, Jing-Hua; Matsuda, Fumihiko; Jang, Hye-Mi; Yoon, Kyungheon; Medina-Gomez, Carolina; Pitsillides, Achilleas; Hottenga, Jouke Jan; Willemsen, Gonneke; Wood, Andrew R; Ji, Yingji; Gao, Zishan; Haworth, Simon; Mitchell, Ruth E; Chai, Jin Fang; Aadahl, Mette; Yao, Jie; Manichaikul, Ani; Warren, Helen R; Ramirez, Julia; Bork-Jensen, Jette; Kårhus, Line L; Goel, Anuj; Sabater-Lleal, Maria; Noordam, Raymond; Sidore, Carlo; Fiorillo, Edoardo; McDaid, Aaron F; Marques-Vidal, Pedro; Wielscher, Matthias; Trompet, Stella; Sattar, Naveed; Møllehave, Line T; Thuesen, Betina H; Munz, Matthias; Zeng, Lingyao; Huang, Jianfeng; Yang, Bin; Poveda, Alaitz; Kurbasic, Azra; Lamina, Claudia; Forer, Lukas; Scholz, Markus; Galesloot, Tessel E; Bradfield, Jonathan P; Daw, E Warwick; Zmuda, Joseph M; Mitchell, Jonathan S; Fuchsberger, Christian; Christensen, Henry; Brody, Jennifer A; Feitosa, Mary F; Wojczynski, Mary K; Preuss, Michael; Mangino, Massimo; Christofidou, Paraskevi; Verweij, Niek; Benjamins, Jan W; Engmann, Jorgen; Kember, Rachel L; Slieker, Roderick C; Lo, Ken Sin; Zilhao, Nuno R; Le, Phuong; Kleber, Marcus E; Delgado, Graciela E; Huo, Shaofeng; Ikeda, Daisuke D; Iha, Hiroyuki; Yang, Jian; Liu, Jun; Leonard, Hampton L; Marten, Jonathan; Schmidt, Börge; Arendt, Marina; Smyth, Laura J; Cañadas-Garre, Marisa; Wang, Chaolong; Nakatochi, Masahiro; Wong, Andrew; Hutri-Kähönen, Nina; Sim, Xueling; Xia, Rui; Huerta-Chagoya, Alicia; Fernandez-Lopez, Juan Carlos; Lyssenko, Valeriya; Ahmed, Meraj; Jackson, Anne U; Yousri, Noha A; Irvin, Marguerite R; Oldmeadow, Christopher; Kim, Han-Na; Ryu, Seungho; Timmers, Paul R H J; Arbeeva, Liubov; Dorajoo, Rajkumar; Lange, Leslie A; Chai, Xiaoran; Prasad, Gauri; Lorés-Motta, Laura; Pauper, Marc; Long, Jirong; Li, Xiaohui; Theusch, Elizabeth; Takeuchi, Fumihiko; Spracklen, Cassandra N; Loukola, Anu; Bollepalli, Sailalitha; Warner, Sophie C; Wang, Ya Xing; Wei, Wen B; Nutile, Teresa; Ruggiero, Daniela; Sung, Yun Ju; Hung, Yi-Jen; Chen, Shufeng; Liu, Fangchao; Yang, Jingyun; Kentistou, Katherine A; Gorski, Mathias; Brumat, Marco; Meidtner, Karina; Bielak, Lawrence F; Smith, Jennifer A; Hebbar, Prashantha; Farmaki, Aliki-Eleni; Hofer, Edith; Lin, Maoxuan; Xue, Chao; Zhang, Jifeng; Concas, Maria Pina; Vaccargiu, Simona; van der Most, Peter J; Pitkänen, Niina; Cade, Brian E; Lee, Jiwon; van der Laan, Sander W; Chitrala, Kumaraswamy Naidu; Weiss, Stefan; Zimmermann, Martina E; Lee, Jong Young; Choi, Hyeok Sun; Nethander, Maria; Freitag-Wolf, Sandra; Southam, Lorraine; Rayner, Nigel W; Wang, Carol A; Lin, Shih-Yi; Wang, Jun-Sing; Couture, Christian; Lyytikäinen, Leo-Pekka; Nikus, Kjell; Cuellar-Partida, Gabriel; Vestergaard, Henrik; Hildalgo, Bertha; Giannakopoulou, Olga; Cai, Qiuyin; Obura, Morgan O; van Setten, Jessica; Li, Xiaoyin; Schwander, Karen; Terzikhan, Natalie; Shin, Jae Hun; Jackson, Rebecca D; Reiner, Alexander P; Martin, Lisa Warsinger; Chen, Zhengming; Li, Liming; Highland, Heather M; Young, Kristin L; Kawaguchi, Takahisa; Thiery, Joachim; Bis, Joshua C; Nadkarni, Girish N; Launer, Lenore J; Li, Huaixing; Nalls, Mike A; Raitakari, Olli T; Ichihara, Sahoko; Wild, Sarah H; Nelson, Christopher P; Campbell, Harry; Jäger, Susanne; Nabika, Toru; Al-Mulla, Fahd; Niinikoski, Harri; Braund, Peter S; Kolcic, Ivana; Kovacs, Peter; Giardoglou, Tota; Katsuya, Tomohiro; Bhatti, Konain Fatima; de Kleijn, Dominique; de Borst, Gert J; Kim, Eung Kweon; Adams, Hieab H H; Ikram, M Arfan; Zhu, Xiaofeng; Asselbergs, Folkert W; Kraaijeveld, Adriaan O; Beulens, Joline W J; Shu, Xiao-Ou; Rallidis, Loukianos S; Pedersen, Oluf; Hansen, Torben; Mitchell, Paul; Hewitt, Alex W; Kähönen, Mika; Pérusse, Louis; Bouchard, Claude; Tönjes, Anke; Chen, Yii-Der Ida; Pennell, Craig E; Mori, Trevor A; Lieb, Wolfgang; Franke, Andre; Ohlsson, Claes; Mellström, Dan; Cho, Yoon Shin; Lee, Hyejin; Yuan, Jian-Min; Koh, Woon-Puay; Rhee, Sang Youl; Woo, Jeong-Taek; Heid, Iris M; Stark, Klaus J; Völzke, Henry; Homuth, Georg; Evans, Michele K; Zonderman, Alan B; Polasek, Ozren; Pasterkamp, Gerard; Hoefer, Imo E; Redline, Susan; Pahkala, Katja; Oldehinkel, Albertine J; Snieder, Harold; Biino, Ginevra; Schmidt, Reinhold; Schmidt, Helena; Chen, Y Eugene; Bandinelli, Stefania; Dedoussis, George; Thanaraj, Thangavel Alphonse; Kardia, Sharon L R; Kato, Norihiro; Schulze, Matthias B; Girotto, Giorgia; Jung, Bettina; Böger, Carsten A; Joshi, Peter K; Bennett, David A; De Jager, Philip L; Lu, Xiangfeng; Mamakou, Vasiliki; Brown, Morris; Caulfield, Mark J; Munroe, Patricia B; Guo, Xiuqing; Ciullo, Marina; Jonas, Jost B; Samani, Nilesh J; Kaprio, Jaakko; Pajukanta, Päivi; Adair, Linda S; Bechayda, Sonny Augustin; de Silva, H Janaka; Wickremasinghe, Ananda R; Krauss, Ronald M; Wu, Jer-Yuarn; Zheng, Wei; den Hollander, Anneke I; Bharadwaj, Dwaipayan; Correa, Adolfo; Wilson, James G; Lind, Lars; Heng, Chew-Kiat; Nelson, Amanda E; Golightly, Yvonne M; Wilson, James F; Penninx, Brenda; Kim, Hyung-Lae; Attia, John; Scott, Rodney J; Rao, D C; Arnett, Donna K; Hunt, Steven C; Walker, Mark; Koistinen, Heikki A; Chandak, Giriraj R; Yajnik, Chittaranjan S; Mercader, Josep M; Tusié-Luna, Teresa; Aguilar-Salinas, Carlos A; Villalpando, Clicerio Gonzalez; Orozco, Lorena; Fornage, Myriam; Tai, E Shyong; van Dam, Rob M; Lehtimäki, Terho; Chaturvedi, Nish; Yokota, Mitsuhiro; Liu, Jianjun; Reilly, Dermot F; McKnight, Amy Jayne; Kee, Frank; Jöckel, Karl-Heinz; McCarthy, Mark I; Palmer, Colin N A; Vitart, Veronique; Hayward, Caroline; Simonsick, Eleanor; van Duijn, Cornelia M; Lu, Fan; Qu, Jia; Hishigaki, Haretsugu; Lin, Xu; März, Winfried; Parra, Esteban J; Cruz, Miguel; Gudnason, Vilmundur; Tardif, Jean-Claude; Lettre, Guillaume; ‘t Hart, Leen M; Elders, Petra J M; Damrauer, Scott M; Kumari, Meena; Kivimaki, Mika; van der Harst, Pim; Spector, Tim D; Loos, Ruth J F; Province, Michael A; Psaty, Bruce M; Brandslund, Ivan; Pramstaller, Peter P; Christensen, Kaare; Ripatti, Samuli; Widén, Elisabeth; Hakonarson, Hakon; Grant, Struan F A; Kiemeney, Lambertus A L M; de Graaf, Jacqueline; Loeffler, Markus; Kronenberg, Florian; Gu, Dongfeng; Erdmann, Jeanette; Schunkert, Heribert; Franks, Paul W; Linneberg, Allan; Jukema, J Wouter; Khera, Amit V; Männikkö, Minna; Jarvelin, Marjo-Riitta; Kutalik, Zoltan; Cucca, Francesco; Mook-Kanamori, Dennis O; van Dijk, Ko Willems; Watkins, Hugh; Strachan, David P; Grarup, Niels; Sever, Peter; Poulter, Neil; Rotter, Jerome I; Dantoft, Thomas M; Karpe, Fredrik; Neville, Matt J; Timpson, Nicholas J; Cheng, Ching-Yu; Wong, Tien-Yin; Khor, Chiea Chuen; Sabanayagam, Charumathi; Peters, Annette; Gieger, Christian; Hattersley, Andrew T; Pedersen, Nancy L; Magnusson, Patrik K E; Boomsma, Dorret I; de Geus, Eco J C; Cupples, L Adrienne; van Meurs, Joyce B J; Ghanbari, Mohsen; Gordon-Larsen, Penny; Huang, Wei; Kim, Young Jin; Tabara, Yasuharu; Wareham, Nicholas J; Langenberg, Claudia; Zeggini, Eleftheria; Kuusisto, Johanna; Laakso, Markku; Ingelsson, Erik; Abecasis, Goncalo; Chambers, John C; Kooner, Jaspal S; de Vries, Paul S; Morrison, Alanna C; North, Kari E; Daviglus, Martha; Kraft, Peter; Martin, Nicholas G; Whitfield, John B; Abbas, Shahid; Saleheen, Danish; Walters, Robin G; Holmes, Michael V; Black, Corri; Smith, Blair H; Justice, Anne E; Baras, Aris; Buring, Julie E; Ridker, Paul M; Chasman, Daniel I; Kooperberg, Charles; Wei, Wei-Qi; Jarvik, Gail P; Namjou, Bahram; Hayes, M Geoffrey; Ritchie, Marylyn D; Jousilahti, Pekka; Salomaa, Veikko; Hveem, Kristian; Åsvold, Bjørn Olav; Kubo, Michiaki; Kamatani, Yoichiro; Okada, Yukinori; Murakami, Yoshinori; Thorsteinsdottir, Unnur; Stefansson, Kari; Ho, Yuk-Lam; Lynch, Julie A; Rader, Daniel J; Tsao, Philip S; Chang, Kyong-Mi; Cho, Kelly; O’Donnell, Christopher J; Gaziano, John M; Wilson, Peter; Rotimi, Charles N; Hazelhurst, Scott; Ramsay, Michèle; Trembath, Richard C; van Heel, David A; Tamiya, Gen; Yamamoto, Masayuki; Kim, Bong-Jo; Mohlke, Karen L; Frayling, Timothy M; Hirschhorn, Joel N; Kathiresan, Sekar; , ; , ; Boehnke, Michael; Natarajan, Pradeep; Peloso, Gina M; Brown, Christopher D; Morris, Andrew P; Assimes, Themistocles L; Deloukas, Panos; Sun, Yan V; Willer, Cristen J
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