Quantitative prediction of right ventricular and size and function from the electrocardiogram.

Link: https://doi.org/10.1101/2023.04.25.23289130
Authors: Duong, Son Q; Vaid, Akhil; Vy, Ha My Thi; Butler, Liam R; Lampert, Joshua; Pass, Robert H; Charney, Alexander W; Narula, Jagat; Khera, Rohan; Greenspan, Hayit; Gelb, Bruce D; Do, Ron; Nadkarni, Girish

Abstract: Right ventricular ejection fraction (RVEF) and end-diastolic volume (RVEDV) are not readily assessed through traditional modalities. Deep-learning enabled 12-lead electrocardiogram analysis (DL-ECG) for estimation of RV size or function is unexplored. DL-ECG analysis can accurately identify significant RV dysfunction and dilation both overall and in key subgroups. Predicted RVEF is independently associated with clinical outcome.