Posts Tagged ‘4research’
Helicopter emergency medical services (HEMS) response to out-of-hospital cardiac arrest (OHCA) in the United States.
Link: https://doi.org/10.1016/j.resplu.2024.100658 Authors: Shekhar, Aditya C; Auten, Michael; Abbott, Ethan E; McCartin, Michael; Blumen, Ira J Abstract: Helicopter emergency medical services (HEMS) are used in the United States and globally to respond to patients with critical illness and victims of traumatic injury. Relatively limited research has examined their role in responding to out-of-hospital cardiac arrests…
Read MoreMachine Learning Quantification of Pulmonary Regurgitation Fraction from Echocardiography.
Link: https://doi.org/10.1007/s00246-024-03511-y Authors: Cohen, Jennifer; Duong, Son Q; Arivazhagan, Naveen; Barris, David M; Bebiya, Surkhay; Castaldo, Rosalie; Gayanilo, Marjorie; Hopkins, Kali; Kailas, Maya; Kong, Grace; Ma, Xiye; Marshall, Molly; Paul, Erin A; Tan, Melanie; Yau, Jen Lie; Nadkarni, Girish N; Ezon, David Abstract: Assessment of pulmonary regurgitation (PR) guides treatment for patients with congenital heart…
Read MoreMachine learning derived serum creatinine trajectories in acute kidney injury in critically ill patients with sepsis.
Link: https://doi.org/10.1186/s13054-024-04935-x Authors: Takkavatakarn, Kullaya; Oh, Wonsuk; Chan, Lili; Hofer, Ira; Shawwa, Khaled; Kraft, Monica; Shah, Neomi; Kohli-Seth, Roopa; Nadkarni, Girish N; Sakhuja, Ankit Abstract: Current classification for acute kidney injury (AKI) in critically ill patients with sepsis relies only on its severity-measured by maximum creatinine which overlooks inherent complexities and longitudinal evaluation of this…
Read MoreDivergent landscapes of A-to-I editing in postmortem and living human brain.
Link: https://doi.org/10.1101/2024.05.06.24306763 Authors: de Los Santos, Miguel Rodriguez; Kopell, Brian H; Grice, Ariela Buxbaum; Ganesh, Gauri; Yang, Andy; Amini, Pardis; Liharska, Lora E; Vornholt, Eric; Fullard, John F; Dong, Pengfei; Park, Eric; Zipkowitz, Sarah; Kaji, Deepak A; Thompson, Ryan C; Liu, Donjing; Park, You Jeong; Cheng, Esther; Ziafat, Kimia; Moya, Emily; Fennessy, Brian; Wilkins, Lillian;…
Read MoreInfant out-of-hospital cardiac arrest during nights and weekends.
Link: https://doi.org/S0735-6757(24)00224-9 Authors: Shekhar, Aditya C; Childers, Molly K; Abbott, Ethan E; Kimbrell, Joshua; Coute, Ryan A; Mader, Timothy J; Mann, N Clay; Madhok, Manu Abstract: A growing body of evidence suggests outcomes for cardiac arrest in adults are worse during nights and weekends when compared with daytime and weekdays. Similar research has not yet…
Read MoreLongitudinal Plasma Metabolome Patterns and Relation to Kidney Function and Proteinuria in Pediatric CKD.
Link: https://doi.org/10.2215/CJN.0000000000000463 Authors: Lee, Arthur M; Xu, Yunwen; Hu, Jian; Xiao, Rui; Hooper, Stephen R; Hartung, Erum A; Coresh, Josef; Rhee, Eugene P; Vasan, Ramachandran S; Kimmel, Paul L; Warady, Bradley A; Furth, Susan L; Denburg, Michelle R; , Abstract: Longitudinal untargeted metabolomics. Children with CKD have a circulating metabolome that changes over time. Understanding…
Read MoreCharacterizing cell type specific transcriptional differences between the living and postmortem human brain.
Link: https://doi.org/10.1101/2024.05.01.24306590 Authors: Vornholt, Eric; Liharska, Lora E; Cheng, Esther; Hashemi, Alice; Park, You Jeong; Ziafat, Kimia; Wilkins, Lillian; Silk, Hannah; Linares, Lisa M; Thompson, Ryan C; Sullivan, Brendan; Moya, Emily; Nadkarni, Girish N; Sebra, Robert; Schadt, Eric E; Kopell, Brian H; Charney, Alexander W; Beckmann, Noam D Abstract: Single-nucleus RNA sequencing (snRNA-seq) is often…
Read MoreA clustering approach to improve our understanding of the genetic and phenotypic complexity of chronic kidney disease.
Link: https://doi.org/10.1038/s41598-024-59747-4 Authors: Eoli, A; Ibing, S; Schurmann, C; Nadkarni, G N; Heyne, H O; Böttinger, E Abstract: Chronic kidney disease (CKD) is a complex disorder that causes a gradual loss of kidney function, affecting approximately 9.1% of the world’s population. Here, we use a soft-clustering algorithm to deconstruct its genetic heterogeneity. First, we selected…
Read MoreNeuropsychiatric complications of coronavirus disease 2019: Mount Sinai Health System cohort study.
Link: https://doi.org/10.1007/s00415-024-12370-9 Authors: Gururangan, Kapil; Peschansky, Veronica J; Van Hyfte, Grace; Agarwal, Parul; Blank, Leah J; Mathew, Brian; Goldstein, Jonathan; Kwon, Churl-Su; McCarthy, Louise; Cohen, Ariella; Chan, Andy Ho Wing; Deng, Pojen; Dhamoon, Mandip; Gutzwiller, Eveline; Hao, Qing; He, Celestine; Klenofsky, Britany; Lemus, Hernan Nicolas; Marcuse, Lara; Navis, Allison; Heredia Nunez, Wilson D; Luckey, Mallory…
Read MoreThe Association of Racial Residential Segregation and Survival After Out-of-Hospital Cardiac Arrest in the United States.
Link: https://doi.org/10.1101/2024.04.22.24306186 Authors: Abbott, Ethan E; Buckler, David G; Shekhar, Aditya C; Landry, Elizabeth; Abella, Benjamin S; Richardson, Lynne D; Zebrowski, Alexis M; , Abstract: Residential segregation has been identified as drivers of disparities in health outcomes, but further work is needed to understand this association with clinical outcomes for out-of-hospital cardiac arrest (OHCA). We…
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