Posts Tagged ‘Cardiology’
Allostatic load predicts racial disparities in intracerebral hemorrhage cognitive outcomes.
Link: https://doi.org/10.1038/s41598-022-20987-x Authors: Harris, Jennifer; Boehme, Amelia; Chan, Luisa; Moats, Harmon; Dugue, Rachelle; Izeogu, Chigozirim; Pavol, Marykay A; Naqvi, Imama A; Williams, Olajide; Marshall, Randolph S Abstract: A large portion of stroke disparities remains unexplained, even after adjusting for demographic, comorbidity, and health care access variables. There is a critical need to close this knowledge…
Read MoreHuman WDR5 promotes breast cancer growth and metastasis via KMT2-independent translation regulation.
Link: https://doi.org/10.7554/eLife.78163 Authors: Cai, Wesley L; Chen, Jocelyn Fang-Yi; Chen, Huacui; Wingrove, Emily; Kurley, Sarah J; Chan, Lok Hei; Zhang, Meiling; Arnal-Estape, Anna; Zhao, Minghui; Balabaki, Amer; Li, Wenxue; Yu, Xufen; Krop, Ethan D; Dou, Yali; Liu, Yansheng; Jin, Jian; Westbrook, Thomas F; Nguyen, Don X; Yan, Qin Abstract: Metastatic breast cancer remains a major…
Read MoreEnhancing convolutional neural network predictions of electrocardiograms with left ventricular dysfunction using a novel sub-waveform representation.
Link: https://doi.org/10.1016/j.cvdhj.2022.07.074 Authors: Honarvar, Hossein; Agarwal, Chirag; Somani, Sulaiman; Vaid, Akhil; Lampert, Joshua; Wanyan, Tingyi; Reddy, Vivek Y; Nadkarni, Girish N; Miotto, Riccardo; Zitnik, Marinka; Wang, Fei; Glicksberg, Benjamin S Abstract: Electrocardiogram (ECG) deep learning (DL) has promise to improve the outcomes of patients with cardiovascular abnormalities. In ECG DL, researchers often use convolutional neural…
Read MoreAutomated Determination of Left Ventricular Function Using Electrocardiogram Data in Patients on Maintenance Hemodialysis.
Link: https://doi.org/10.2215/CJN.16481221 Authors: Vaid, Akhil; Jiang, Joy J; Sawant, Ashwin; Singh, Karandeep; Kovatch, Patricia; Charney, Alexander W; Charytan, David M; Divers, Jasmin; Glicksberg, Benjamin S; Chan, Lili; Nadkarni, Girish N Abstract: Left ventricular ejection fraction is disrupted in patients on maintenance hemodialysis and can be estimated using deep learning models on electrocardiograms. Smaller sample sizes…
Read MoreInsights From a Large-Scale Whole-Genome Sequencing Study of Systolic Blood Pressure, Diastolic Blood Pressure, and Hypertension.
Link: https://doi.org/10.1161/HYPERTENSIONAHA.122.19324 Authors: Kelly, Tanika N; Sun, Xiao; He, Karen Y; Brown, Michael R; Taliun, Sarah A Gagliano; Hellwege, Jacklyn N; Irvin, Marguerite R; Mi, Xuenan; Brody, Jennifer A; Franceschini, Nora; Guo, Xiuqing; Hwang, Shih-Jen; de Vries, Paul S; Gao, Yan; Moscati, Arden; Nadkarni, Girish N; Yanek, Lisa R; Elfassy, Tali; Smith, Jennifer A; Chung,…
Read MoreDesign and rationale of GUARDD-US: A pragmatic, randomized trial of genetic testing for APOL1 and pharmacogenomic predictors of antihypertensive efficacy in patients with hypertension.
Link: https://doi.org/S1551-7144(22)00139-2 Authors: Eadon, Michael T; Cavanaugh, Kerri L; Orlando, Lori A; Christian, David; Chakraborty, Hrishikesh; Steen-Burrell, Kady-Ann; Merrill, Peter; Seo, Janet; Hauser, Diane; Singh, Rajbir; Beasley, Cherry Maynor; Fuloria, Jyotsna; Kitzman, Heather; Parker, Alexander S; Ramos, Michelle; Ong, Henry H; Elwood, Erica N; Lynch, Sheryl E; Clermont, Sabrina; Cicali, Emily J; Starostik, Petr; Pratt,…
Read MoreHispanic ethnicity and mortality among critically ill patients with COVID-19.
Link: https://doi.org/10.1371/journal.pone.0268022 Authors: Ricardo, Ana C; Chen, Jinsong; Toth-Manikowski, Stephanie M; Meza, Natalie; Joo, Min; Gupta, Shruti; Lazarous, Deepa G; Leaf, David E; Lash, James P; , Abstract: Hispanic persons living in the United States (U.S.) are at higher risk of infection and death from coronavirus disease 2019 (COVID-19) compared with non-Hispanic persons. Whether this…
Read MoreGenome-first recall of healthy individuals by polygenic risk score reveals differences in coronary artery calcium.
Link: https://doi.org/S0002-8703(22)00081-3 Authors: Forrest, Iain S; Chan, Lili; Chaudhary, Kumardeep; Saha, Aparna; Wen, Huei Hsun; Cepin, Cristina Liriano; Marquez-Luna, Carla; Rocheleau, Ghislain; Cho, Judy; Narula, Jagat; Nadkarni, Girish N; Do, Ron Abstract: Genetic risk for coronary artery disease (CAD) is commonly measured with polygenic risk scores (PRS); yet, the relationship of atherosclerotic burden with PRS…
Read MoreAssociation of Uremic Solutes With Cardiovascular Death in Diabetic Kidney Disease.
Link: https://doi.org/S0272-6386(22)00577-7 Authors: Sapa, Hima; Gutiérrez, Orlando M; Shlipak, Michael G; Katz, Ronit; Ix, Joachim H; Sarnak, Mark J; Cushman, Mary; Rhee, Eugene P; Kimmel, Paul L; Vasan, Ramachandran S; Schrauben, Sarah J; Feldman, Harold I; Seegmiller, Jesse C; Brunengraber, Henri; Hostetter, Thomas H; Schelling, Jeffrey R; , Abstract: Cardiovascular disease (CVD) is a major…
Read MoreElectroencephalography at the height of a pandemic: EEG findings in patients with COVID-19.
Link: https://doi.org/S1388-2457(22)00190-0 Authors: Tantillo, Gabriela B; Jetté, Nathalie; Gururangan, Kapil; Agarwal, Parul; Marcuse, Lara; Singh, Anuradha; Goldstein, Jonathan; Kwon, Churl-Su; Dhamoon, Mandip S; Navis, Allison; Nadkarni, Girish N; Charney, Alexander W; Young, James J; Blank, Leah J; Fields, Madeline; Yoo, Ji Yeoun Abstract: To characterize continuous video electroencephalogram (VEEG) findings of hospitalized COVID-19 patients. We…
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