Clinical predictors of response to methotrexate in patients with rheumatoid arthritis: a machine learning approach using clinical trial data.

Link: https://doi.org/10.1186/s13075-022-02851-5 Authors: Duong, Stephanie Q; Crowson, Cynthia S; Athreya, Arjun; Atkinson, Elizabeth J; Davis, John M; Warrington, Kenneth J; Matteson, Eric L; Weinshilboum, Richard; Wang, Liewei; Myasoedova, Elena Abstract: Methotrexate is the preferred initial disease-modifying antirheumatic drug (DMARD) for rheumatoid arthritis (RA). However, clinically useful tools for individualized prediction of response to methotrexate treatment…

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