A machine learning model identifies patients in need of autoimmune disease testing using electronic health records.

Link: https://doi.org/10.1038/s41467-023-37996-7 Authors: Forrest, Iain S; Petrazzini, Ben O; Duffy, Áine; Park, Joshua K; O’Neal, Anya J; Jordan, Daniel M; Rocheleau, Ghislain; Nadkarni, Girish N; Cho, Judy H; Blazer, Ashira D; Do, Ron Abstract: Systemic autoimmune rheumatic diseases (SARDs) can lead to irreversible damage if left untreated, yet these patients often endure long diagnostic journeys…

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Joint Modeling of Clinical and Biomarker Data in Acute Kidney Injury Defines Unique Subphenotypes with Differing Outcomes.

Link: https://doi.org/10.2215/CJN.0000000000000156 Authors: Vasquez-Rios, George; Oh, Wonsuk; Lee, Samuel; Bhatraju, Pavan; Mansour, Sherry G; Moledina, Dennis G; Gulamali, Faris F; Siew, Edward D; Garg, Amit X; Sarder, Pinaki; Chinchilli, Vernon M; Kaufman, James S; Hsu, Chi-Yuan; Liu, Kathleen D; Kimmel, Paul L; Go, Alan S; Wurfel, Mark M; Himmelfarb, Jonathan; Parikh, Chirag R; Coca, Steven…

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Randomized Trial of Anticoagulation Strategies for Noncritically Ill Patients Hospitalized With COVID-19.

Link: https://doi.org/S0735-1097(23)04527-8 Authors: Stone, Gregg W; Farkouh, Michael E; Lala, Anuradha; Tinuoye, Elizabeth; Dressler, Ovidiu; Moreno, Pedro R; Palacios, Igor F; Goodman, Shaun G; Esper, Rodrigo B; Abizaid, Alexandre; Varade, Deepak; Betancur, Juan F; Ricalde, Alejandro; Payro, Gerardo; Castellano, José María; Hung, Ivan F N; Nadkarni, Girish N; Giustino, Gennaro; Godoy, Lucas C; Feinman, Jason;…

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Hospital-Level Variation in Death for Critically Ill Patients with COVID-19.

Link: https://doi.org/10.1164/rccm.202012-4547OC Authors: Churpek, Matthew M; Gupta, Shruti; Spicer, Alexandra B; Parker, William F; Fahrenbach, John; Brenner, Samantha K; Leaf, David E; , Abstract: Variation in hospital mortality has been described for coronavirus disease 2019 (COVID-19), but the factors that explain these differences remain unclear. Our objective was to utilize a large, nationally representative dataset…

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Prone Positioning and Survival in Mechanically Ventilated Patients With Coronavirus Disease 2019-Related Respiratory Failure.

Link: https://doi.org/10.1097/CCM.0000000000004938 Authors: Mathews, Kusum S; Soh, Howard; Shaefi, Shahzad; Wang, Wei; Bose, Sonali; Coca, Steven; Gupta, Shruti; Hayek, Salim S; Srivastava, Anand; Brenner, Samantha K; Radbel, Jared; Green, Adam; Sutherland, Anne; Leonberg-Yoo, Amanda; Shehata, Alexandre; Schenck, Edward J; Short, Samuel A P; Hernán, Miguel A; Chan, Lili; Leaf, David E; , Abstract: Therapies for…

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Evaluation and management of COVID-19-related severity in people with type 2 diabetes.

Link: https://doi.org/10.1136/bmjdrc-2021-002299 Authors: Wang, Bowen; Glicksberg, Benjamin S; Nadkarni, Girish N; Vashishth, Deepak Abstract: People with type 2 diabetes (T2D) have an increased rate of hospitalization and mortality related to COVID-19. To identify ahead of time those who are at risk of developing severe diseases and potentially in need of intensive care, we investigated the…

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Factors Associated With Death in Critically Ill Patients With Coronavirus Disease 2019 in the US.

Link: https://doi.org/10.1001/jamainternmed.2020.3596 Authors: Gupta, Shruti; Hayek, Salim S; Wang, Wei; Chan, Lili; Mathews, Kusum S; Melamed, Michal L; Brenner, Samantha K; Leonberg-Yoo, Amanda; Schenck, Edward J; Radbel, Jared; Reiser, Jochen; Bansal, Anip; Srivastava, Anand; Zhou, Yan; Sutherland, Anne; Green, Adam; Shehata, Alexandre M; Goyal, Nitender; Vijayan, Anitha; Velez, Juan Carlos Q; Shaefi, Shahzad; Parikh, Chirag…

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Association Between Early Treatment With Tocilizumab and Mortality Among Critically Ill Patients With COVID-19.

Link: https://doi.org/10.1001/jamainternmed.2020.6252 Authors: Gupta, Shruti; Wang, Wei; Hayek, Salim S; Chan, Lili; Mathews, Kusum S; Melamed, Michal L; Brenner, Samantha K; Leonberg-Yoo, Amanda; Schenck, Edward J; Radbel, Jared; Reiser, Jochen; Bansal, Anip; Srivastava, Anand; Zhou, Yan; Finkel, Diana; Green, Adam; Mallappallil, Mary; Faugno, Anthony J; Zhang, Jingjing; Velez, Juan Carlos Q; Shaefi, Shahzad; Parikh, Chirag…

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Genetic hallmarks of recurrent/metastatic adenoid cystic carcinoma.

Link: https://doi.org/128227 Authors: Ho, Allen S; Ochoa, Angelica; Jayakumaran, Gowtham; Zehir, Ahmet; Valero Mayor, Cristina; Tepe, Justin; Makarov, Vladimir; Dalin, Martin G; He, Jie; Bailey, Mark; Montesion, Meagan; Ross, Jeffrey S; Miller, Vincent A; Chan, Lindsay; Ganly, Ian; Dogan, Snjezana; Katabi, Nora; Tsipouras, Petros; Ha, Patrick; Agrawal, Nishant; Solit, David B; Futreal, P Andrew; El…

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Development of a Definition of Postacute Sequelae of SARS-CoV-2 Infection.

Link: https://doi.org/10.1001/jama.2023.8823 Authors: Thaweethai, Tanayott; Jolley, Sarah E; Karlson, Elizabeth W; Levitan, Emily B; Levy, Bruce; McComsey, Grace A; McCorkell, Lisa; Nadkarni, Girish N; Parthasarathy, Sairam; Singh, Upinder; Walker, Tiffany A; Selvaggi, Caitlin A; Shinnick, Daniel J; Schulte, Carolin C M; Atchley-Challenner, Rachel; Alba, George A; Alicic, Radica; Altman, Natasha; Anglin, Khamal; Argueta, Urania; Ashktorab,…

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