Posts Tagged ‘Critical Care’
Continuous Kidney Replacement Therapy of the Future: Innovations in Information Technology, Data Analytics, and Quality Assurance Systems.
Link: https://doi.org/S1548-5595(21)00031-8 Authors: Neyra, Javier A; Nadkarni, Girish N Abstract: Continuous kidney replacement therapy is commonly used in the critically ill population. Despite the recent development in continuous kidney replacement therapy technology and clinical informatics, many aspects of continuous kidney replacement therapy delivery are still not fully standardized, and quality assurance programs for the provision…
Read MoreUsing sequence clustering to identify clinically relevant subphenotypes in patients with COVID-19 admitted to the intensive care unit.
Link: https://doi.org/10.1093/jamia/ocab252 Authors: Oh, Wonsuk; Jayaraman, Pushkala; Sawant, Ashwin S; Chan, Lili; Levin, Matthew A; Charney, Alexander W; Kovatch, Patricia; Glicksberg, Benjamin S; Nadkarni, Girish N Abstract: The novel coronavirus disease 2019 (COVID-19) has heterogenous clinical courses, indicating that there might be distinct subphenotypes in critically ill patients. Although prior research has identified these subphenotypes,…
Read MorePopulation-Based Penetrance of Deleterious Clinical Variants.
Link: https://doi.org/10.1001/jama.2021.23686 Authors: Forrest, Iain S; Chaudhary, Kumardeep; Vy, Ha My T; Petrazzini, Ben O; Bafna, Shantanu; Jordan, Daniel M; Rocheleau, Ghislain; Loos, Ruth J F; Nadkarni, Girish N; Cho, Judy H; Do, Ron Abstract: Population-based assessment of disease risk associated with gene variants informs clinical decisions and risk stratification approaches. To evaluate the population-based…
Read MoreDeep learning and the electrocardiogram: review of the current state-of-the-art.
Link: https://doi.org/10.1093/europace/euaa377 Authors: Somani, Sulaiman; Russak, Adam J; Richter, Felix; Zhao, Shan; Vaid, Akhil; Chaudhry, Fayzan; De Freitas, Jessica K; Naik, Nidhi; Miotto, Riccardo; Nadkarni, Girish N; Narula, Jagat; Argulian, Edgar; Glicksberg, Benjamin S Abstract: In the recent decade, deep learning, a subset of artificial intelligence and machine learning, has been used to identify patterns…
Read MoreHospital-Level Variation in Death for Critically Ill Patients with COVID-19.
Link: https://doi.org/10.1164/rccm.202012-4547OC Authors: Churpek, Matthew M; Gupta, Shruti; Spicer, Alexandra B; Parker, William F; Fahrenbach, John; Brenner, Samantha K; Leaf, David E; , Abstract: Variation in hospital mortality has been described for coronavirus disease 2019 (COVID-19), but the factors that explain these differences remain unclear. Our objective was to utilize a large, nationally representative dataset…
Read MoreProne Positioning and Survival in Mechanically Ventilated Patients With Coronavirus Disease 2019-Related Respiratory Failure.
Link: https://doi.org/10.1097/CCM.0000000000004938 Authors: Mathews, Kusum S; Soh, Howard; Shaefi, Shahzad; Wang, Wei; Bose, Sonali; Coca, Steven; Gupta, Shruti; Hayek, Salim S; Srivastava, Anand; Brenner, Samantha K; Radbel, Jared; Green, Adam; Sutherland, Anne; Leonberg-Yoo, Amanda; Shehata, Alexandre; Schenck, Edward J; Short, Samuel A P; Hernán, Miguel A; Chan, Lili; Leaf, David E; , Abstract: Therapies for…
Read MoreEvaluation and management of COVID-19-related severity in people with type 2 diabetes.
Link: https://doi.org/10.1136/bmjdrc-2021-002299 Authors: Wang, Bowen; Glicksberg, Benjamin S; Nadkarni, Girish N; Vashishth, Deepak Abstract: People with type 2 diabetes (T2D) have an increased rate of hospitalization and mortality related to COVID-19. To identify ahead of time those who are at risk of developing severe diseases and potentially in need of intensive care, we investigated the…
Read MoreFactors Associated With Death in Critically Ill Patients With Coronavirus Disease 2019 in the US.
Link: https://doi.org/10.1001/jamainternmed.2020.3596 Authors: Gupta, Shruti; Hayek, Salim S; Wang, Wei; Chan, Lili; Mathews, Kusum S; Melamed, Michal L; Brenner, Samantha K; Leonberg-Yoo, Amanda; Schenck, Edward J; Radbel, Jared; Reiser, Jochen; Bansal, Anip; Srivastava, Anand; Zhou, Yan; Sutherland, Anne; Green, Adam; Shehata, Alexandre M; Goyal, Nitender; Vijayan, Anitha; Velez, Juan Carlos Q; Shaefi, Shahzad; Parikh, Chirag…
Read MoreAssociation Between Early Treatment With Tocilizumab and Mortality Among Critically Ill Patients With COVID-19.
Link: https://doi.org/10.1001/jamainternmed.2020.6252 Authors: Gupta, Shruti; Wang, Wei; Hayek, Salim S; Chan, Lili; Mathews, Kusum S; Melamed, Michal L; Brenner, Samantha K; Leonberg-Yoo, Amanda; Schenck, Edward J; Radbel, Jared; Reiser, Jochen; Bansal, Anip; Srivastava, Anand; Zhou, Yan; Finkel, Diana; Green, Adam; Mallappallil, Mary; Faugno, Anthony J; Zhang, Jingjing; Velez, Juan Carlos Q; Shaefi, Shahzad; Parikh, Chirag…
Read MoreEvaluation of the portability of computable phenotypes with natural language processing in the eMERGE network.
Link: https://doi.org/10.1038/s41598-023-27481-y Authors: Pacheco, Jennifer A; Rasmussen, Luke V; Wiley, Ken; Person, Thomas Nate; Cronkite, David J; Sohn, Sunghwan; Murphy, Shawn; Gundelach, Justin H; Gainer, Vivian; Castro, Victor M; Liu, Cong; Mentch, Frank; Lingren, Todd; Sundaresan, Agnes S; Eickelberg, Garrett; Willis, Valerie; Furmanchuk, Al’ona; Patel, Roshan; Carrell, David S; Deng, Yu; Walton, Nephi; Satterfield, Benjamin…
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