Polygenic prediction of preeclampsia and gestational hypertension.

By Amir Safavi | May 29, 2023 |

Link: https://doi.org/10.1038/s41591-023-02374-9 Authors: Honigberg, Michael C; Truong, Buu; Khan, Raiyan R; Xiao, Brenda; Bhatta, Laxmi; Vy, Ha My T; Guerrero, Rafael F; Schuermans, Art; Selvaraj, Margaret Sunitha; Patel, Aniruddh P; Koyama, Satoshi; Cho, So Mi Jemma; Vellarikkal, Shamsudheen Karuthedath; Trinder, Mark; Urbut, Sarah M; Gray, Kathryn J; Brumpton, Ben M; Patil, Snehal; Zöllner, Sebastian; Antopia,…

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Distinct subtypes of polycystic ovary syndrome with novel genetic associations: An unsupervised, phenotypic clustering analysis.

By Amir Safavi | June 23, 2020 |

Link: https://doi.org/10.1371/journal.pmed.1003132 Authors: Dapas, Matthew; Lin, Frederick T J; Nadkarni, Girish N; Sisk, Ryan; Legro, Richard S; Urbanek, Margrit; Hayes, M Geoffrey; Dunaif, Andrea Abstract: Polycystic ovary syndrome (PCOS) is a common, complex genetic disorder affecting up to 15% of reproductive-age women worldwide, depending on the diagnostic criteria applied. These diagnostic criteria are based on…

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