The Kidney Failure Risk Equation: Evaluation of Novel Input Variables including eGFR Estimated Using the CKD-EPI 2021 Equation in 59 Cohorts.

Link: https://doi.org/10.1681/ASN.0000000000000050 Authors: Grams, Morgan E; Brunskill, Nigel J; Ballew, Shoshana H; Sang, Yingying; Coresh, Josef; Matsushita, Kunihiro; Surapaneni, Aditya; Bell, Samira; Carrero, Juan J; Chodick, Gabriel; Evans, Marie; Heerspink, Hiddo J L; Inker, Lesley A; Iseki, Kunitoshi; Kalra, Philip A; Kirchner, H Lester; Lee, Brian J; Levin, Adeera; Major, Rupert W; Medcalf, James; Nadkarni,…

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Cannabis Use and CKD: Epidemiological Associations and Mendelian Randomization.

Link: https://doi.org/10.1016/j.xkme.2022.100582 Authors: Dellepiane, Sergio; Paranjpe, Ishan; Rajagopal, Madhumitha; Kamat, Samir; O’Hagan, Ross; Gulamali, Faris; Rein, Joshua L; Charney, Alexander W; Do, Ron; Coca, Steven; Glicksberg, Benjamin S; Nadkarni, Girish N Abstract: The association between cannabis use and chronic kidney disease (CKD) is controversial. We aimed to assess association of CKD with cannabis use in…

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Artificial Intelligence and Machine Learning in Perioperative Acute Kidney Injury.

Link: https://doi.org/S2949-8139(22)00001-5 Authors: Takkavatakarn, Kullaya; Hofer, Ira S Abstract: Acute kidney injury (AKI) is a common complication after a surgery, especially in cardiac and aortic procedures, and has a significant impact on morbidity and mortality. Early identification of high-risk patients and providing effective prevention and therapeutic approach are the main strategies for reducing the possibility…

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Unplanned 30-Day Readmission Rates for Autosomal Dominant Polycystic Kidney Disease: Insight from the Nationwide Readmissions Database.

Link: https://doi.org/10.1159/000526923 Authors: Saha, Aparna; Ericksen, Paulette; Liriano Cepin, Cristina; Nadkarni, Girish N; Chan, Lili Abstract: Among end-stage kidney disease (ESKD) patients on dialysis with autosomal dominant polycystic kidney disease (ADPKD), relatively little is known about the epidemiology and risk factors for 30-day readmissions in the USA. Therefore, we evaluated the 30-day unplanned readmission rates…

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Laboratory Result Reference Ranges Stratified for Patient-Reported Sex and Ethnicity Are More Closely Associated With Postoperative Outcomes Than Currently Used Reference Ranges: A Retrospective Data Analysis.

Link: https://doi.org/10.1213/ANE.0000000000006229 Authors: Hofer, Ira S; Lee, Andrew; Grogan, Tristan; Lucero, Jennifer; Cannesson, Maxime Abstract: A single laboratory range for all individuals may fail to take into account underlying physiologic differences based on sex and genetic factors. We hypothesized that laboratory distributions differ based on self-reported sex and ethnicity and that ranges stratified by these…

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Higher Symptom Frequency and Severity After the Long Interdialytic Interval in Patients on Maintenance Intermittent Hemodialysis.

Link: https://doi.org/10.1016/j.ekir.2022.09.032 Authors: Chauhan, Kinsuk; Wen, Huei Hsun; Gupta, Neepa; Nadkarni, Girish; Coca, Steven; Chan, Lili Abstract: Patients on intermittent hemodialysis (HD) have a high symptom burden. Though studies report higher hospitalizations and mortality after the long interdialytic interval, whether symptoms vary based on the interdialytic interval is unclear. This is a prospective observational study…

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Proteomic Characterization of Acute Kidney Injury in Patients Hospitalized with SARS-CoV2 Infection.

Link: https://doi.org/10.1101/2021.12.09.21267548 Authors: Paranjpe, Ishan; Jayaraman, Pushkala; Su, Chen-Yang; Zhou, Sirui; Chen, Steven; Thompson, Ryan; Del Valle, Diane Marie; Kenigsberg, Ephraim; Zhao, Shan; Jaladanki, Suraj; Chaudhary, Kumardeep; Ascolillo, Steven; Vaid, Akhil; Kumar, Arvind; Kozlova, Edgar; Paranjpe, Manish; O’Hagan, Ross; Kamat, Samir; Gulamali, Faris F; Kauffman, Justin; Xie, Hui; Harris, Joceyln; Patel, Manishkumar; Argueta, Kimberly; Batchelor,…

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