Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations.

Link: https://doi.org/S0092-8674(20)30822-9 Authors: Chen, Ming-Huei; Raffield, Laura M; Mousas, Abdou; Sakaue, Saori; Huffman, Jennifer E; Moscati, Arden; Trivedi, Bhavi; Jiang, Tao; Akbari, Parsa; Vuckovic, Dragana; Bao, Erik L; Zhong, Xue; Manansala, Regina; Laplante, Véronique; Chen, Minhui; Lo, Ken Sin; Qian, Huijun; Lareau, Caleb A; Beaudoin, Mélissa; Hunt, Karen A; Akiyama, Masato; Bartz, Traci M; Ben-Shlomo,…

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Maternal metabolic, immune, and microbial systems in late pregnancy vary with malnutrition in mice.

Link: https://doi.org/10.1093/biolre/ioy002 Authors: Connor, Kristin L; Chehoud, Christel; Altrichter, Adam; Chan, Luisa; DeSantis, Todd Z; Lye, Stephen J Abstract: Malnutrition is a global threat to pregnancy health and impacts offspring development. Establishing an optimal pregnancy environment requires the coordination of maternal metabolic and immune pathways, which converge at the gut. Diet, metabolic, and immune dysfunctions…

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Author Correction: Metabolic gatekeeper function of B-lymphoid transcription factors.

Link: https://doi.org/10.1038/s41586-018-0164-5 Authors: Chan, Lai N; Chen, Zhengshan; Braas, Daniel; Lee, Jae-Woong; Xiao, Gang; Geng, Huimin; Cosgun, Kadriye Nehir; Hurtz, Christian; Shojaee, Seyedmehdi; Cazzaniga, Valeria; Schjerven, Hilde; Ernst, Thomas; Hochhaus, Andreas; Kornblau, Steven M; Konopleva, Marina; Pufall, Miles A; Cazzaniga, Giovanni; Liu, Grace J; Milne, Thomas A; Koeffler, H Phillip; Ross, Theodora S; Sánchez-García, Isidro;…

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Rising incidence and prevalence of systemic lupus erythematosus: a population-based study over four decades.

Link: https://doi.org/10.1136/annrheumdis-2022-222276 Authors: Duarte-García, Alí; Hocaoglu, Mehmet; Valenzuela-Almada, Maria; Osei-Onomah, Shirley-Ann; Dabit, Jesse Y; Sanchez-Rodriguez, Alain; Duong, Stephanie Q; Giblon, Rachel E; Langenfeld, Hannah E; Alarcón, Graciela S; Helmick, Charles G; Crowson, Cynthia S Abstract: To determine the trends in incidence, prevalence and mortality of systemic lupus erythematosus (SLE) in a US population over four…

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StudyU: A Platform for Designing and Conducting Innovative Digital N-of-1 Trials.

Link: https://doi.org/10.2196/35884 Authors: Konigorski, Stefan; Wernicke, Sarah; Slosarek, Tamara; Zenner, Alexander M; Strelow, Nils; Ruether, Darius F; Henschel, Florian; Manaswini, Manisha; Pottbäcker, Fabian; Edelman, Jonathan A; Owoyele, Babajide; Danieletto, Matteo; Golden, Eddye; Zweig, Micol; Nadkarni, Girish N; Böttinger, Erwin Abstract: N-of-1 trials are the gold standard study design to evaluate individual treatment effects and derive…

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Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation.

Link: https://doi.org/10.1038/s41588-022-01058-3 Authors: Mahajan, Anubha; Spracklen, Cassandra N; Zhang, Weihua; Ng, Maggie C Y; Petty, Lauren E; Kitajima, Hidetoshi; Yu, Grace Z; Rüeger, Sina; Speidel, Leo; Kim, Young Jin; Horikoshi, Momoko; Mercader, Josep M; Taliun, Daniel; Moon, Sanghoon; Kwak, Soo-Heon; Robertson, Neil R; Rayner, Nigel W; Loh, Marie; Kim, Bong-Jo; Chiou, Joshua; Miguel-Escalada, Irene; Della…

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Incidence, prevalence and mortality of chronic periaortitis: a population-based study.

Link: https://doi.org/10.55563/clinexprheumatol/0v8l4j Authors: Koster, Matthew J; Ghaffar, Umar; Duong, Stephanie Q; Crowson, Cynthia S; Burke, Michelle M; Viers, Boyd R; Potretzke, Aaron M; Bjarnason, Haraldur; Warrington, Kenneth J Abstract: To evaluate the epidemiology, presentation and outcomes of patients with chronic periaortitis from 1998 through 2018. An inception cohort of patients with incident chronic periaortitis from…

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The trans-ancestral genomic architecture of glycemic traits.

Link: https://doi.org/10.1038/s41588-021-00852-9 Authors: Chen, Ji; Spracklen, Cassandra N; Marenne, Gaëlle; Varshney, Arushi; Corbin, Laura J; Luan, Jian’an; Willems, Sara M; Wu, Ying; Zhang, Xiaoshuai; Horikoshi, Momoko; Boutin, Thibaud S; Mägi, Reedik; Waage, Johannes; Li-Gao, Ruifang; Chan, Kei Hang Katie; Yao, Jie; Anasanti, Mila D; Chu, Audrey Y; Claringbould, Annique; Heikkinen, Jani; Hong, Jaeyoung; Hottenga, Jouke-Jan;…

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