Conversion of Urine Protein-Creatinine Ratio or Urine Dipstick Protein to Urine Albumin-Creatinine Ratio for Use in Chronic Kidney Disease Screening and Prognosis : An Individual Participant-Based Meta-analysis.

Link: https://doi.org/10.7326/M20-0529 Authors: Sumida, Keiichi; Nadkarni, Girish N; Grams, Morgan E; Sang, Yingying; Ballew, Shoshana H; Coresh, Josef; Matsushita, Kunihiro; Surapaneni, Aditya; Brunskill, Nigel; Chadban, Steve J; Chang, Alex R; Cirillo, Massimo; Daratha, Kenn B; Gansevoort, Ron T; Garg, Amit X; Iacoviello, Licia; Kayama, Takamasa; Konta, Tsuneo; Kovesdy, Csaba P; Lash, James; Lee, Brian J;…

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Distinct subtypes of polycystic ovary syndrome with novel genetic associations: An unsupervised, phenotypic clustering analysis.

Link: https://doi.org/10.1371/journal.pmed.1003132 Authors: Dapas, Matthew; Lin, Frederick T J; Nadkarni, Girish N; Sisk, Ryan; Legro, Richard S; Urbanek, Margrit; Hayes, M Geoffrey; Dunaif, Andrea Abstract: Polycystic ovary syndrome (PCOS) is a common, complex genetic disorder affecting up to 15% of reproductive-age women worldwide, depending on the diagnostic criteria applied. These diagnostic criteria are based on…

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Derivation and validation of genome-wide polygenic score for urinary tract stone diagnosis.

Link: https://doi.org/S0085-2538(20)30641-4 Authors: Paranjpe, Ishan; Tsao, Noah; Judy, Renae; Paranjpe, Manish; Chaudhary, Kumardeep; Klarin, Derek; Forrest, Iain; O’Hagan, Ross; Kapoor, Arjun; Pfail, John; Jaladanki, Suraj; Chaudhry, Fayzan; Vaid, Akhil; Duy, Phan Q; , ; , ; He, John Cijiang; Glicksberg, Benjamin S; Coca, Steven G; Gupta, Mantu; Do, Ron; Damrauer, Scott M; Nadkarni, Girish N…

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Prevalence and Impact of Myocardial Injury in Patients Hospitalized With COVID-19 Infection.

Link: https://doi.org/S0735-1097(20)35552-2 Authors: Lala, Anuradha; Johnson, Kipp W; Januzzi, James L; Russak, Adam J; Paranjpe, Ishan; Richter, Felix; Zhao, Shan; Somani, Sulaiman; Van Vleck, Tielman; Vaid, Akhil; Chaudhry, Fayzan; De Freitas, Jessica K; Fayad, Zahi A; Pinney, Sean P; Levin, Matthew; Charney, Alexander; Bagiella, Emilia; Narula, Jagat; Glicksberg, Benjamin S; Nadkarni, Girish; Mancini, Donna M;…

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Machine Learning in Cardiology-Ensuring Clinical Impact Lives Up to the Hype.

Link: https://doi.org/10.1177/1074248420928651 Authors: Russak, Adam J; Chaudhry, Farhan; De Freitas, Jessica K; Baron, Garrett; Chaudhry, Fayzan F; Bienstock, Solomon; Paranjpe, Ishan; Vaid, Akhil; Ali, Mohsin; Zhao, Shan; Somani, Sulaiman; Richter, Felix; Bawa, Tejeshwar; Levy, Phillip D; Miotto, Riccardo; Nadkarni, Girish N; Johnson, Kipp W; Glicksberg, Benjamin S Abstract: Despite substantial advances in the study, treatment,…

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The effect of LRRK2 loss-of-function variants in humans.

Link: https://doi.org/10.1038/s41591-020-0893-5 Authors: Whiffin, Nicola; Armean, Irina M; Kleinman, Aaron; Marshall, Jamie L; Minikel, Eric V; Goodrich, Julia K; Quaife, Nicholas M; Cole, Joanne B; Wang, Qingbo; Karczewski, Konrad J; Cummings, Beryl B; Francioli, Laurent; Laricchia, Kristen; Guan, Anna; Alipanahi, Babak; Morrison, Peter; Baptista, Marco A S; Merchant, Kalpana M; , ; , ; Ware,…

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