Posts by Amir Safavi
Hospital-Level Variation in Death for Critically Ill Patients with COVID-19.
Link: https://doi.org/10.1164/rccm.202012-4547OC Authors: Churpek, Matthew M; Gupta, Shruti; Spicer, Alexandra B; Parker, William F; Fahrenbach, John; Brenner, Samantha K; Leaf, David E; , Abstract: Variation in hospital mortality has been described for coronavirus disease 2019 (COVID-19), but the factors that explain these differences remain unclear. Our objective was to utilize a large, nationally representative dataset…
Read MoreEvaluation and management of COVID-19-related severity in people with type 2 diabetes.
Link: https://doi.org/10.1136/bmjdrc-2021-002299 Authors: Wang, Bowen; Glicksberg, Benjamin S; Nadkarni, Girish N; Vashishth, Deepak Abstract: People with type 2 diabetes (T2D) have an increased rate of hospitalization and mortality related to COVID-19. To identify ahead of time those who are at risk of developing severe diseases and potentially in need of intensive care, we investigated the…
Read MoreAuthor Correction: Sampling the host response to SARS-CoV-2 in hospitals under siege.
Link: https://doi.org/10.1038/s41591-021-01247-3 Authors: Charney, Alexander W; Simons, Nicole W; Mouskas, Konstantinos; Lepow, Lauren; Cheng, Esther; Le Berichel, Jessica; Chang, Christie; Marvin, Robert; Del Valle, Diane Marie; Calorossi, Sharlene; Lansky, Alona; Walker, Laura; Patel, Manishkumar; Xie, Hui; Yi, Nancy; Yu, Alex; Kang, Gurpawan; Mendoza, Anthony; Liharska, Lora E; Moya, Emily; Hartnett, Matthew; Hatem, Sandra; Wilkins, Lillian;…
Read MoreAuthor Correction: The power of genetic diversity in genome-wide association studies of lipids.
Link: https://doi.org/10.1038/s41586-023-06194-2 Authors: Graham, Sarah E; Clarke, Shoa L; Wu, Kuan-Han H; Kanoni, Stavroula; Zajac, Greg J M; Ramdas, Shweta; Surakka, Ida; Ntalla, Ioanna; Vedantam, Sailaja; Winkler, Thomas W; Locke, Adam E; Marouli, Eirini; Hwang, Mi Yeong; Han, Sohee; Narita, Akira; Choudhury, Ananyo; Bentley, Amy R; Ekoru, Kenneth; Verma, Anurag; Trivedi, Bhavi; Martin, Hilary C;…
Read MoreMaternal metabolic, immune, and microbial systems in late pregnancy vary with malnutrition in mice.
Link: https://doi.org/10.1093/biolre/ioy002 Authors: Connor, Kristin L; Chehoud, Christel; Altrichter, Adam; Chan, Luisa; DeSantis, Todd Z; Lye, Stephen J Abstract: Malnutrition is a global threat to pregnancy health and impacts offspring development. Establishing an optimal pregnancy environment requires the coordination of maternal metabolic and immune pathways, which converge at the gut. Diet, metabolic, and immune dysfunctions…
Read MoreGenome-wide polygenic risk score for retinopathy of type 2 diabetes.
Link: https://doi.org/10.1093/hmg/ddab067 Authors: Forrest, Iain S; Chaudhary, Kumardeep; Paranjpe, Ishan; Vy, Ha My T; Marquez-Luna, Carla; Rocheleau, Ghislain; Saha, Aparna; Chan, Lili; Van Vleck, Tielman; Loos, Ruth J F; Cho, Judy; Pasquale, Louis R; Nadkarni, Girish N; Do, Ron Abstract: Diabetic retinopathy (DR) is a common consequence in type 2 diabetes (T2D) and a leading…
Read MoreSerum potassium and adverse outcomes across the range of kidney function: a CKD Prognosis Consortium meta-analysis.
Link: https://doi.org/10.1093/eurheartj/ehy100 Authors: Kovesdy, Csaba P; Matsushita, Kunihiro; Sang, Yingying; Brunskill, Nigel J; Carrero, Juan J; Chodick, Gabriel; Hasegawa, Takeshi; Heerspink, Hiddo L; Hirayama, Atsushi; Landman, Gijs W D; Levin, Adeera; Nitsch, Dorothea; Wheeler, David C; Coresh, Josef; Hallan, Stein I; Shalev, Varda; Grams, Morgan E; , Abstract: Both hypo- and hyperkalaemia can have immediate…
Read MoreIncluding measures of chronic kidney disease to improve cardiovascular risk prediction by SCORE2 and SCORE2-OP.
Link: https://doi.org/10.1093/eurjpc/zwac176 Authors: Matsushita, Kunihiro; Kaptoge, Stephen; Hageman, Steven H J; Sang, Yingying; Ballew, Shoshana H; Grams, Morgan E; Surapaneni, Aditya; Sun, Luanluan; Arnlov, Johan; Bozic, Milica; Brenner, Hermann; Brunskill, Nigel J; Chang, Alex R; Chinnadurai, Rajkumar; Cirillo, Massimo; Correa, Adolfo; Ebert, Natalie; Eckardt, Kai-Uwe; Gansevoort, Ron T; Gutierrez, Orlando; Hadaegh, Farzad; He, Jiang; Hwang,…
Read MoreUsing sequence clustering to identify clinically relevant subphenotypes in patients with COVID-19 admitted to the intensive care unit.
Link: https://doi.org/10.1093/jamia/ocab252 Authors: Oh, Wonsuk; Jayaraman, Pushkala; Sawant, Ashwin S; Chan, Lili; Levin, Matthew A; Charney, Alexander W; Kovatch, Patricia; Glicksberg, Benjamin S; Nadkarni, Girish N Abstract: The novel coronavirus disease 2019 (COVID-19) has heterogenous clinical courses, indicating that there might be distinct subphenotypes in critically ill patients. Although prior research has identified these subphenotypes,…
Read MoreAssociation between intradialytic central venous oxygen saturation and ultrafiltration volume in chronic hemodialysis patients.
Link: https://doi.org/10.1093/ndt/gfx271 Authors: Zhang, Hanjie; Chan, Lili; Meyring-Wösten, Anna; Campos, Israel; Preciado, Priscila; Kooman, Jeroen P; van der Sande, Frank M; Fuertinger, Doris; Thijssen, Stephan; Kotanko, Peter Abstract: Cardiac disease is highly prevalent in hemodialysis (HD) patients. Decreased tissue perfusion, including cardiac, due to high ultrafiltration volumes (UFVs) is considered to be one of the…
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