4research
Machine learning-based marker for coronary artery disease: derivation and validation in two longitudinal cohorts.
Link: https://doi.org/S0140-6736(22)02079-7 Authors: Forrest, Iain S; Petrazzini, Ben O; Duffy, Áine; Park, Joshua K; Marquez-Luna, Carla; Jordan, Daniel M; Rocheleau, Ghislain; Cho, Judy H; Rosenson, Robert S; Narula, Jagat; Nadkarni, Girish N; Do, Ron Abstract: Binary diagnosis of coronary artery disease does not preserve the complexity of disease or quantify its severity or its associated…
Read MoreAutoencoders for sample size estimation for fully connected neural network classifiers.
Link: https://doi.org/10.1038/s41746-022-00728-0 Authors: Gulamali, Faris F; Sawant, Ashwin S; Kovatch, Patricia; Glicksberg, Benjamin; Charney, Alexander; Nadkarni, Girish N; Oermann, Eric Abstract: Sample size estimation is a crucial step in experimental design but is understudied in the context of deep learning. Currently, estimating the quantity of labeled data needed to train a classifier to a desired…
Read MoreCannabis Use and CKD: Epidemiological Associations and Mendelian Randomization.
Link: https://doi.org/10.1016/j.xkme.2022.100582 Authors: Dellepiane, Sergio; Paranjpe, Ishan; Rajagopal, Madhumitha; Kamat, Samir; O’Hagan, Ross; Gulamali, Faris; Rein, Joshua L; Charney, Alexander W; Do, Ron; Coca, Steven; Glicksberg, Benjamin S; Nadkarni, Girish N Abstract: The association between cannabis use and chronic kidney disease (CKD) is controversial. We aimed to assess association of CKD with cannabis use in…
Read MoreMolecular states during acute COVID-19 reveal distinct etiologies of long-term sequelae.
Link: https://doi.org/10.1038/s41591-022-02107-4 Authors: Thompson, Ryan C; Simons, Nicole W; Wilkins, Lillian; Cheng, Esther; Del Valle, Diane Marie; Hoffman, Gabriel E; Cervia, Carlo; Fennessy, Brian; Mouskas, Konstantinos; Francoeur, Nancy J; Johnson, Jessica S; Lepow, Lauren; Le Berichel, Jessica; Chang, Christie; Beckmann, Aviva G; Wang, Ying-Chih; Nie, Kai; Zaki, Nicholas; Tuballes, Kevin; Barcessat, Vanessa; Cedillo, Mario A;…
Read MoreArtificial Intelligence and Machine Learning in Perioperative Acute Kidney Injury.
Link: https://doi.org/S2949-8139(22)00001-5 Authors: Takkavatakarn, Kullaya; Hofer, Ira S Abstract: Acute kidney injury (AKI) is a common complication after a surgery, especially in cardiac and aortic procedures, and has a significant impact on morbidity and mortality. Early identification of high-risk patients and providing effective prevention and therapeutic approach are the main strategies for reducing the possibility…
Read MoreGeneralizability of an acute kidney injury prediction model across health systems.
Link: https://doi.org/10.1038/s42256-022-00563-8 Authors: Cao, Jie; Zhang, Xiaosong; Shahinian, Vahakn; Yin, Huiying; Steffick, Diane; Saran, Rajiv; Crowley, Susan; Mathis, Michael; Nadkarni, Girish N; Heung, Michael; Singh, Karandeep Abstract:
Read MoreShort-term prediction of coronary artery disease using serum metabolomic patterns.
Link: https://doi.org/10.1016/j.ahjo.2022.100232 Authors: Petrazzini, Ben Omega; Vaid, Akhil; Park, Joshua K; Marquez-Luna, Carla; Vy, Ha My; Saha, Aparna; Chaudhary, Kumardeep; Cho, Judy; Chan, Lili; Argulian, Edgar; Narula, Jagat; Nadkarni, Girish; Do, Ron Abstract:
Read MoreGenome-wide association and multi-trait analyses characterize the common genetic architecture of heart failure.
Link: https://doi.org/10.1038/s41467-022-34216-6 Authors: Levin, Michael G; Tsao, Noah L; Singhal, Pankhuri; Liu, Chang; Vy, Ha My T; Paranjpe, Ishan; Backman, Joshua D; Bellomo, Tiffany R; Bone, William P; Biddinger, Kiran J; Hui, Qin; Dikilitas, Ozan; Satterfield, Benjamin A; Yang, Yifan; Morley, Michael P; Bradford, Yuki; Burke, Megan; Reza, Nosheen; Charest, Brian; , ; Judy, Renae…
Read MoreEpidemiology of Cutaneous Lupus Erythematosus Among Adults Over Four Decades (1976-2018): A Lupus Midwest Network (LUMEN) Study.
Link: https://doi.org/S0025-6196(22)00379-2 Authors: Hocaoğlu, Mehmet; Davis, Mark Denis P; Osei-Onomah, Shirley-Ann; Valenzuela-Almada, Maria O; Dabit, Jesse Y; Duong, Stephanie Q; Yang, Jeffrey X; Helmick, Charles G; Crowson, Cynthia; Duarte-García, Alí Abstract: To characterize the epidemiological trends and mortality of cutaneous lupus erythematosus (CLE) between 1976 and 2018 in Olmsted County, Minnesota. In this retrospective population-based…
Read MoreUnplanned 30-Day Readmission Rates for Autosomal Dominant Polycystic Kidney Disease: Insight from the Nationwide Readmissions Database.
Link: https://doi.org/10.1159/000526923 Authors: Saha, Aparna; Ericksen, Paulette; Liriano Cepin, Cristina; Nadkarni, Girish N; Chan, Lili Abstract: Among end-stage kidney disease (ESKD) patients on dialysis with autosomal dominant polycystic kidney disease (ADPKD), relatively little is known about the epidemiology and risk factors for 30-day readmissions in the USA. Therefore, we evaluated the 30-day unplanned readmission rates…
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