4research
Quantitative prediction of right ventricular and size and function from the electrocardiogram.
Link: https://doi.org/10.1101/2023.04.25.23289130 Authors: Duong, Son Q; Vaid, Akhil; Vy, Ha My Thi; Butler, Liam R; Lampert, Joshua; Pass, Robert H; Charney, Alexander W; Narula, Jagat; Khera, Rohan; Greenspan, Hayit; Gelb, Bruce D; Do, Ron; Nadkarni, Girish Abstract: Right ventricular ejection fraction (RVEF) and end-diastolic volume (RVEDV) are not readily assessed through traditional modalities. Deep-learning enabled…
Read MoreA machine learning model identifies patients in need of autoimmune disease testing using electronic health records.
Link: https://doi.org/10.1038/s41467-023-37996-7 Authors: Forrest, Iain S; Petrazzini, Ben O; Duffy, Áine; Park, Joshua K; O’Neal, Anya J; Jordan, Daniel M; Rocheleau, Ghislain; Nadkarni, Girish N; Cho, Judy H; Blazer, Ashira D; Do, Ron Abstract: Systemic autoimmune rheumatic diseases (SARDs) can lead to irreversible damage if left untreated, yet these patients often endure long diagnostic journeys…
Read MoreJoint Modeling of Clinical and Biomarker Data in Acute Kidney Injury Defines Unique Subphenotypes with Differing Outcomes.
Link: https://doi.org/10.2215/CJN.0000000000000156 Authors: Vasquez-Rios, George; Oh, Wonsuk; Lee, Samuel; Bhatraju, Pavan; Mansour, Sherry G; Moledina, Dennis G; Gulamali, Faris F; Siew, Edward D; Garg, Amit X; Sarder, Pinaki; Chinchilli, Vernon M; Kaufman, James S; Hsu, Chi-Yuan; Liu, Kathleen D; Kimmel, Paul L; Go, Alan S; Wurfel, Mark M; Himmelfarb, Jonathan; Parikh, Chirag R; Coca, Steven…
Read MoreInhaled Corticosteroids Rarely Prescribed at Emergency Department Discharge Despite Low Rates of Follow-Up Care.
Link: https://doi.org/S0736-4679(23)00062-8 Authors: Kligler, Sophie Karwoska; Vargas-Torres, Carmen; Abbott, Ethan E; Lin, Michelle P Abstract: Guidelines recommend an inhaled corticosteroid (ICS) prescription on emergency department (ED) discharge after acute asthma exacerbations. We sought to identify rates and predictors of ICS prescription at ED discharge. Secondary outcomes included ICS prescription rates in a high-risk subgroup, outpatient…
Read MoreProteomic Characterization of Acute Kidney Injury in Patients Hospitalized with SARS-CoV2 Infection.
Link: https://doi.org/10.21203/rs.3.rs-2379226/v1 Authors: Nadkami, Girish; Paranjpe, Ishan; Jayaraman, Pushkala; Su, Chen-Yang; Zhou, Sirui; Chen, Steven; Valle, Diane Del; Thompson, Ryan; Kenigsberg, Ephraim; Zhao, Shan; Jaladanki, Suraj; Chaudhary, Kumardeep; Ascolillo, Steven; Vaid, Akhil; Gonzalez-Kozlova, Edgar; Kumar, Arvind; Paranjpe, Manish; O’Hagan, Ross; Kamat, Samir; Gulamali, Faris; Kauffman, Justin; Xie, Hui; Harris, Joceyln; Patel, Manishkumar; Argueta, Kimberly; Batchelor,…
Read MoreRandomized Trial of Anticoagulation Strategies for Noncritically Ill Patients Hospitalized With COVID-19.
Link: https://doi.org/S0735-1097(23)04527-8 Authors: Stone, Gregg W; Farkouh, Michael E; Lala, Anuradha; Tinuoye, Elizabeth; Dressler, Ovidiu; Moreno, Pedro R; Palacios, Igor F; Goodman, Shaun G; Esper, Rodrigo B; Abizaid, Alexandre; Varade, Deepak; Betancur, Juan F; Ricalde, Alejandro; Payro, Gerardo; Castellano, José María; Hung, Ivan F N; Nadkarni, Girish N; Giustino, Gennaro; Godoy, Lucas C; Feinman, Jason;…
Read MoreTrends of Acute Kidney Injury Requiring Dialysis Among Hospitalized Patients Undergoing Invasive Electrophysiology Procedures.
Link: https://doi.org/10.1097/HPC.0000000000000214 Authors: Wen, Yumeng; Hosseini Dehkordi, Seyed Hamed; Wei, Xin; Lucas, Claire Huang; Paranjpe, Ishan; Yan, Dexi; Gholitabar, Farid; Mehta, Davendra; Chan, Lili; Meisels, Ira Abstract: Electrophysiology (EP) procedures carry the risk of kidney injury due to contrast/hemodynamic fluctuations. We aim to evaluate the national epidemiology of acute kidney injury requiring dialysis (AKI-D) in…
Read MorePotential kidney toxicity from the antiviral drug tenofovir: new indications, new formulations, and a new prodrug.
Link: https://doi.org/10.1097/MNH.0000000000000392 Authors: Chan, Lili; Asriel, Benjamin; Eaton, Ellen F; Wyatt, Christina M Abstract: The antiviral agent tenofovir is highly effective for the treatment of HIV and hepatitis B virus infections, and the older prodrug tenofovir disoproxil fumarate (TDF) is also a component of daily preexposure prophylaxis (PrEP) to reduce the risk of HIV infection…
Read MoreApplications of machine learning methods in kidney disease: hope or hype?
Link: https://doi.org/10.1097/MNH.0000000000000604 Authors: Chan, Lili; Vaid, Akhil; Nadkarni, Girish N Abstract: The universal adoption of electronic health records, improvement in technology, and the availability of continuous monitoring has generated large quantities of healthcare data. Machine learning is increasingly adopted by nephrology researchers to analyze this data in order to improve the care of their patients.…
Read MoreAnalysis of Biomarkers Within the Initial 2 Years Posttransplant and 5-Year Kidney Transplant Outcomes: Results From Clinical Trials in Organ Transplantation-17.
Link: https://doi.org/10.1097/TP.0000000000002026 Authors: Faddoul, Geovani; Nadkarni, Girish N; Bridges, Nancy D; Goebel, Jens; Hricik, Donald E; Formica, Richard; Menon, Madhav C; Morrison, Yvonne; Murphy, Barbara; Newell, Kenneth; Nickerson, Peter; Poggio, Emilio D; Rush, David; Heeger, Peter S; , Abstract: An early posttransplant biomarker/surrogate marker for kidney allograft loss has the potential to guide targeted interventions.…
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