Population-Based Penetrance of Deleterious Clinical Variants.

Link: https://doi.org/10.1001/jama.2021.23686 Authors: Forrest, Iain S; Chaudhary, Kumardeep; Vy, Ha My T; Petrazzini, Ben O; Bafna, Shantanu; Jordan, Daniel M; Rocheleau, Ghislain; Loos, Ruth J F; Nadkarni, Girish N; Cho, Judy H; Do, Ron Abstract: Population-based assessment of disease risk associated with gene variants informs clinical decisions and risk stratification approaches. To evaluate the population-based…

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