Posts Tagged ‘COVID-19’
Integrated multiomics implicates dysregulation of ECM and cell adhesion pathways as drivers of severe COVID-associated kidney injury.
Link: https://doi.org/10.1101/2024.03.18.24304401 Authors: Anandakrishnan, Nanditha; Yi, Zhengzi; Sun, Zeguo; Liu, Tong; Haydak, Jonathan; Eddy, Sean; Jayaraman, Pushkala; DeFronzo, Stefanie; Saha, Aparna; Sun, Qian; Yang, Dai; Mendoza, Anthony; Mosoyan, Gohar; Wen, Huei Hsun; Schaub, Jennifer A; Fu, Jia; Kehrer, Thomas; Menon, Rajasree; Otto, Edgar A; Godfrey, Bradley; Suarez-Farinas, Mayte; Leffters, Sean; Twumasi, Akosua; Meliambro, Kristin; Charney,…
Read MoreA novel method leveraging time series data to improve subphenotyping and application in critically ill patients with COVID-19.
Link: https://doi.org/S0933-3657(23)00264-6 Authors: Oh, Wonsuk; Jayaraman, Pushkala; Tandon, Pranai; Chaddha, Udit S; Kovatch, Patricia; Charney, Alexander W; Glicksberg, Benjamin S; Nadkarni, Girish N Abstract: Computational subphenotyping, a data-driven approach to understanding disease subtypes, is a prominent topic in medical research. Numerous ongoing studies are dedicated to developing advanced computational subphenotyping methods for cross-sectional data. However,…
Read MorePeripheral Transcriptomics in Acute and Long-Term Kidney Dysfunction in SARS-CoV2 Infection.
Link: https://doi.org/10.1101/2023.10.25.23297469 Authors: Jayaraman, Pushkala; Rajagopal, Madhumitha; Paranjpe, Ishan; Liharska, Lora; Suarez-Farinas, Mayte; Thompson, Ryan; Del Valle, Diane Marie; Beckmann, Noam; Oh, Wonsuk; Gulamali, Faris F; Kauffman, Justin; Gonzalez-Kozlova, Edgar; Dellepiane, Sergio; Vasquez-Rios, George; Vaid, Akhil; Jiang, Joy; Chen, Annie; Sakhuja, Ankit; Chen, Steven; Kenigsberg, Ephraim; He, John Cijiang; Coca, Steven G; Chan, Lili; Schadt,…
Read MoreComparing ChatGPT and GPT-4 performance in USMLE soft skill assessments.
Link: https://doi.org/10.1038/s41598-023-43436-9 Authors: Brin, Dana; Sorin, Vera; Vaid, Akhil; Soroush, Ali; Glicksberg, Benjamin S; Charney, Alexander W; Nadkarni, Girish; Klang, Eyal Abstract: The United States Medical Licensing Examination (USMLE) has been a subject of performance study for artificial intelligence (AI) models. However, their performance on questions involving USMLE soft skills remains unexplored. This study aimed…
Read MoreDevelopment of a decentralized cohort for studying post-acute sequelae of COVID-19 in India in the Data4life Study.
Link: https://doi.org/10.1038/s43856-023-00349-y Authors: Schilling, Josh; Shokouhi, Sepideh; Montgomery, Aisha; Nadkarni, Girish N; Charney, Alexander W; Shanker, Anil; Singh, Rajbir; Jhaveri, Kenar; Singh, Karandeep S; Khadke, Prashant; Jain, Praduman Abstract: Decentralized, digital health studies can provide real-world evidence of the lasting effects of COVID-19 on physical, socioeconomic, psychological, and social determinant factors of health in India. Existing…
Read MoreTiming of invasive mechanical ventilation and death in critically ill adults with COVID-19: A multicenter cohort study.
Link: https://doi.org/10.1371/journal.pone.0285748 Authors: Green, Adam; Rachoin, Jean-Sebastien; Schorr, Christa; Dellinger, Phil; Casey, Jonathan D; Park, Isabel; Gupta, Shruti; Baron, Rebecca M; Shaefi, Shahzad; Hunter, Krystal; Leaf, David E; , Abstract: To investigate if the timing of initiation of invasive mechanical ventilation (IMV) for critically ill patients with COVID-19 is associated with mortality. The data for…
Read MoreResearching COVID to Enhance Recovery (RECOVER) adult study protocol: Rationale, objectives, and design.
Link: https://doi.org/10.1371/journal.pone.0286297 Authors: Horwitz, Leora I; Thaweethai, Tanayott; Brosnahan, Shari B; Cicek, Mine S; Fitzgerald, Megan L; Goldman, Jason D; Hess, Rachel; Hodder, S L; Jacoby, Vanessa L; Jordan, Michael R; Krishnan, Jerry A; Laiyemo, Adeyinka O; Metz, Torri D; Nichols, Lauren; Patzer, Rachel E; Sekar, Anisha; Singer, Nora G; Stiles, Lauren E; Taylor, Barbara…
Read MoreProteomic characterization of acute kidney injury in patients hospitalized with SARS-CoV2 infection.
Link: https://doi.org/10.1038/s43856-023-00307-8 Authors: Paranjpe, Ishan; Jayaraman, Pushkala; Su, Chen-Yang; Zhou, Sirui; Chen, Steven; Thompson, Ryan; Del Valle, Diane Marie; Kenigsberg, Ephraim; Zhao, Shan; Jaladanki, Suraj; Chaudhary, Kumardeep; Ascolillo, Steven; Vaid, Akhil; Gonzalez-Kozlova, Edgar; Kauffman, Justin; Kumar, Arvind; Paranjpe, Manish; Hagan, Ross O; Kamat, Samir; Gulamali, Faris F; Xie, Hui; Harris, Joceyln; Patel, Manishkumar; Argueta, Kimberly;…
Read MoreEvaluation of Plasma Biomarkers to Predict Major Adverse Kidney Events in Hospitalized Patients With COVID-19.
Link: https://doi.org/S0272-6386(23)00648-0 Authors: Menez, Steven; Coca, Steven G; Moledina, Dennis G; Wen, Yumeng; Chan, Lili; Thiessen-Philbrook, Heather; Obeid, Wassim; Garibaldi, Brian T; Azeloglu, Evren U; Ugwuowo, Ugochukwu; Sperati, C John; Arend, Lois J; Rosenberg, Avi Z; Kaushal, Madhurima; Jain, Sanjay; Wilson, F Perry; Parikh, Chirag R; , Abstract: Patients hospitalized with COVID-19 are at increased…
Read MoreProteomic Characterization of Acute Kidney Injury in Patients Hospitalized with SARS-CoV2 Infection.
Link: https://doi.org/10.21203/rs.3.rs-2379226/v1 Authors: Nadkami, Girish; Paranjpe, Ishan; Jayaraman, Pushkala; Su, Chen-Yang; Zhou, Sirui; Chen, Steven; Valle, Diane Del; Thompson, Ryan; Kenigsberg, Ephraim; Zhao, Shan; Jaladanki, Suraj; Chaudhary, Kumardeep; Ascolillo, Steven; Vaid, Akhil; Gonzalez-Kozlova, Edgar; Kumar, Arvind; Paranjpe, Manish; O’Hagan, Ross; Kamat, Samir; Gulamali, Faris; Kauffman, Justin; Xie, Hui; Harris, Joceyln; Patel, Manishkumar; Argueta, Kimberly; Batchelor,…
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