Relational Learning Improves Prediction of Mortality in COVID-19 in the Intensive Care Unit.

Link: https://doi.org/10.1109/tbdata.2020.3048644 Authors: Wanyan, Tingyi; Vaid, Akhil; De Freitas, Jessica K; Somani, Sulaiman; Miotto, Riccardo; Nadkarni, Girish N; Azad, Ariful; Ding, Ying; Glicksberg, Benjamin S Abstract: Traditional Machine Learning (ML) models have had limited success in predicting Coronoavirus-19 (COVID-19) outcomes using Electronic Health Record (EHR) data partially due to not effectively capturing the inter-connectivity patterns…

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Intravenous alteplase for stroke with unknown time of onset guided by advanced imaging: systematic review and meta-analysis of individual patient data.

Link: https://doi.org/S0140-6736(20)32163-2 Authors: Thomalla, Götz; Boutitie, Florent; Ma, Henry; Koga, Masatoshi; Ringleb, Peter; Schwamm, Lee H; Wu, Ona; Bendszus, Martin; Bladin, Christopher F; Campbell, Bruce C V; Cheng, Bastian; Churilov, Leonid; Ebinger, Martin; Endres, Matthias; Fiebach, Jochen B; Fukuda-Doi, Mayumi; Inoue, Manabu; Kleinig, Timothy J; Latour, Lawrence L; Lemmens, Robin; Levi, Christopher R; Leys, Didier;…

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SGLT2 Inhibitors: Emerging Roles in the Protection Against Cardiovascular and Kidney Disease Among Diabetic Patients.

Link: https://doi.org/10.2147/IJNRD.S268811 Authors: Vasquez-Rios, George; Nadkarni, Girish N Abstract: Type 2 diabetes mellitus (T2DM) is a prevalent disease with the severe clinical implications including myocardial infarction, stroke, and kidney disease. Therapies focusing on glycemic control in T2DM such as biguanides, sulfonylureas, thiazolidinediones, and insulin-based regimens have largely failed to substantially improve cardiovascular and kidney outcomes.…

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Utilization of Deep Learning for Subphenotype Identification in Sepsis-Associated Acute Kidney Injury.

Link: https://doi.org/10.2215/CJN.09330819 Authors: Chaudhary, Kumardeep; Vaid, Akhil; Duffy, Áine; Paranjpe, Ishan; Jaladanki, Suraj; Paranjpe, Manish; Johnson, Kipp; Gokhale, Avantee; Pattharanitima, Pattharawin; Chauhan, Kinsuk; O’Hagan, Ross; Van Vleck, Tielman; Coca, Steven G; Cooper, Richard; Glicksberg, Benjamin; Bottinger, Erwin P; Chan, Lili; Nadkarni, Girish N Abstract: Sepsis-associated AKI is a heterogeneous clinical entity. We aimed to agnostically…

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AKI in Hospitalized Patients with COVID-19.

Link: https://doi.org/10.1681/ASN.2020050615 Authors: Chan, Lili; Chaudhary, Kumardeep; Saha, Aparna; Chauhan, Kinsuk; Vaid, Akhil; Zhao, Shan; Paranjpe, Ishan; Somani, Sulaiman; Richter, Felix; Miotto, Riccardo; Lala, Anuradha; Kia, Arash; Timsina, Prem; Li, Li; Freeman, Robert; Chen, Rong; Narula, Jagat; Just, Allan C; Horowitz, Carol; Fayad, Zahi; Cordon-Cardo, Carlos; Schadt, Eric; Levin, Matthew A; Reich, David L; Fuster,…

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Distinct subtypes of polycystic ovary syndrome with novel genetic associations: An unsupervised, phenotypic clustering analysis.

Link: https://doi.org/10.1371/journal.pmed.1003132 Authors: Dapas, Matthew; Lin, Frederick T J; Nadkarni, Girish N; Sisk, Ryan; Legro, Richard S; Urbanek, Margrit; Hayes, M Geoffrey; Dunaif, Andrea Abstract: Polycystic ovary syndrome (PCOS) is a common, complex genetic disorder affecting up to 15% of reproductive-age women worldwide, depending on the diagnostic criteria applied. These diagnostic criteria are based on…

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Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017.

Link: https://doi.org/10.1038/s41591-020-0807-6 Authors: , Abstract: A double burden of malnutrition occurs when individuals, household members or communities experience both undernutrition and overweight. Here, we show geospatial estimates of overweight and wasting prevalence among children under 5 years of age in 105 low- and middle-income countries (LMICs) from 2000 to 2017 and aggregate these to policy-relevant…

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Sleep in the Natural Environment: A Pilot Study.

Link: https://doi.org/10.3390/s20051378 Authors: Chaudhry, Fayzan F; Danieletto, Matteo; Golden, Eddye; Scelza, Jerome; Botwin, Greg; Shervey, Mark; De Freitas, Jessica K; Paranjpe, Ishan; Nadkarni, Girish N; Miotto, Riccardo; Glowe, Patricia; Stock, Greg; Percha, Bethany; Zimmerman, Noah; Dudley, Joel T; Glicksberg, Benjamin S Abstract:

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