Development of a federated learning approach to predict acute kidney injury in adult hospitalized patients with COVID-19 in New York City.

Link: https://doi.org/10.1101/2021.07.25.21261105 Authors: Jaladanki, Suraj K; Vaid, Akhil; Sawant, Ashwin S; Xu, Jie; Shah, Kush; Dellepiane, Sergio; Paranjpe, Ishan; Chan, Lili; Kovatch, Patricia; Charney, Alexander W; Wang, Fei; Glicksberg, Benjamin S; Singh, Karandeep; Nadkarni, Girish N Abstract: Federated learning is a technique for training predictive models without sharing patient-level data, thus maintaining data security while…

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Non-invasive ventilation versus mechanical ventilation in hypoxemic patients with COVID-19.

Link: https://doi.org/10.1007/s15010-021-01633-6 Authors: Forrest, Iain S; Jaladanki, Suraj K; Paranjpe, Ishan; Glicksberg, Benjamin S; Nadkarni, Girish N; Do, Ron Abstract: Limited mechanical ventilators (MV) during the Coronavirus disease (COVID-19) pandemic have led to the use of non-invasive ventilation (NIV) in hypoxemic patients, which has not been studied well. We aimed to assess the association of…

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The trans-ancestral genomic architecture of glycemic traits.

Link: https://doi.org/10.1038/s41588-021-00852-9 Authors: Chen, Ji; Spracklen, Cassandra N; Marenne, Gaëlle; Varshney, Arushi; Corbin, Laura J; Luan, Jian’an; Willems, Sara M; Wu, Ying; Zhang, Xiaoshuai; Horikoshi, Momoko; Boutin, Thibaud S; Mägi, Reedik; Waage, Johannes; Li-Gao, Ruifang; Chan, Kei Hang Katie; Yao, Jie; Anasanti, Mila D; Chu, Audrey Y; Claringbould, Annique; Heikkinen, Jani; Hong, Jaeyoung; Hottenga, Jouke-Jan;…

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Impact of institutional routine surveillance endomyocardial biopsy frequency in the first year on rejection and graft survival in pediatric heart transplantation.

Link: https://doi.org/10.1111/petr.14035 Authors: Duong, Son Q; Zhang, Yulin; Hall, Matt; Hollander, Seth A; Thurm, Cary W; Bernstein, Daniel; Feingold, Brian; Godown, Justin; Almond, Christopher Abstract: Routine surveillance biopsy (RSB) is performed to detect asymptomatic acute rejection (AR) after heart transplantation (HT). Variation in pediatric RSB across institutions is high. We examined center-based variation in RSB…

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Identification of Distinct Clinical Subphenotypes in Critically Ill Patients With COVID-19.

Link: https://doi.org/S0012-3692(21)00874-6 Authors: Vasquez, Charles R; Gupta, Shruti; Miano, Todd A; Roche, Meaghan; Hsu, Jesse; Yang, Wei; Holena, Daniel N; Reilly, John P; Schrauben, Sarah J; Leaf, David E; Shashaty, Michael G S; , Abstract: Subphenotypes have been identified in patients with sepsis and ARDS and are associated with different outcomes and responses to therapies.…

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Association of SARS-CoV-2 viral load at admission with in-hospital acute kidney injury: A retrospective cohort study.

Link: https://doi.org/10.1371/journal.pone.0247366 Authors: Paranjpe, Ishan; Chaudhary, Kumardeep; Johnson, Kipp W; Jaladanki, Suraj K; Zhao, Shan; De Freitas, Jessica K; Pujdas, Elisabet; Chaudhry, Fayzan; Bottinger, Erwin P; Levin, Matthew A; Fayad, Zahi A; Charney, Alexander W; Houldsworth, Jane; Cordon-Cardo, Carlos; Glicksberg, Benjamin S; Nadkarni, Girish N Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the…

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Use of Physiological Data From a Wearable Device to Identify SARS-CoV-2 Infection and Symptoms and Predict COVID-19 Diagnosis: Observational Study.

Link: https://doi.org/10.2196/26107 Authors: Hirten, Robert P; Danieletto, Matteo; Tomalin, Lewis; Choi, Katie Hyewon; Zweig, Micol; Golden, Eddye; Kaur, Sparshdeep; Helmus, Drew; Biello, Anthony; Pyzik, Renata; Charney, Alexander; Miotto, Riccardo; Glicksberg, Benjamin S; Levin, Matthew; Nabeel, Ismail; Aberg, Judith; Reich, David; Charney, Dennis; Bottinger, Erwin P; Keefer, Laurie; Suarez-Farinas, Mayte; Nadkarni, Girish N; Fayad, Zahi A…

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Thrombosis, Bleeding, and the Observational Effect of Early Therapeutic Anticoagulation on Survival in Critically Ill Patients With COVID-19.

Link: https://doi.org/10.7326/M20-6739 Authors: Al-Samkari, Hanny; Gupta, Shruti; Leaf, Rebecca Karp; Wang, Wei; Rosovsky, Rachel P; Brenner, Samantha K; Hayek, Salim S; Berlin, Hanna; Kapoor, Rajat; Shaefi, Shahzad; Melamed, Michal L; Sutherland, Anne; Radbel, Jared; Green, Adam; Garibaldi, Brian T; Srivastava, Anand; Leonberg-Yoo, Amanda; Shehata, Alexandre M; Flythe, Jennifer E; Rashidi, Arash; Goyal, Nitender; Chan, Lili;…

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Increasing Prevalence of Frailty and Its Association with Readmission and Mortality Among Hospitalized Patients with IBD.

Link: https://doi.org/10.1007/s10620-020-06746-w Authors: Faye, Adam S; Wen, Timothy; Soroush, Ali; Ananthakrishnan, Ashwin N; Ungaro, Ryan; Lawlor, Garrett; Attenello, Frank J; Mack, William J; Colombel, Jean-Frederic; Lebwohl, Benjamin Abstract: Although age is often used as a clinical risk stratification tool, recent data have suggested that adverse outcomes are driven by frailty rather than chronological age. In…

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Retrospective cohort study of clinical characteristics of 2199 hospitalised patients with COVID-19 in New York City.

Link: https://doi.org/10.1136/bmjopen-2020-040736 Authors: Paranjpe, Ishan; Russak, Adam J; De Freitas, Jessica K; Lala, Anuradha; Miotto, Riccardo; Vaid, Akhil; Johnson, Kipp W; Danieletto, Matteo; Golden, Eddye; Meyer, Dara; Singh, Manbir; Somani, Sulaiman; Kapoor, Arjun; O’Hagan, Ross; Manna, Sayan; Nangia, Udit; Jaladanki, Suraj K; O’Reilly, Paul; Huckins, Laura M; Glowe, Patricia; Kia, Arash; Timsina, Prem; Freeman, Robert…

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