Posts Tagged ‘Nephrology’
The Association of Fenofibrate with Kidney Tubular Injury in a Subgroup of Participants in the ACCORD Trial.
Link: https://doi.org/10.2215/CJN.00370119 Authors: Chauhan, Kinsuk; Nadkarni, Girish N; Debnath, Neha; Chan, Lili; Saha, Aparna; Garg, Amit X; Parikh, Chirag R; Coca, Steven G Abstract:
Read MoreTrends and Racial Disparities of Palliative Care Use among Hospitalized Patients with ESKD on Dialysis.
Link: https://doi.org/10.1681/ASN.2018121256 Authors: Wen, Yumeng; Jiang, Changchuan; Koncicki, Holly M; Horowitz, Carol R; Cooper, Richard S; Saha, Aparna; Coca, Steven G; Nadkarni, Girish N; Chan, Lili Abstract: Study findings show that although palliative care decreases symptom burden, it is still underused in patients with ESKD. Little is known about disparity in use of palliative care…
Read MoreAugmented intelligence with natural language processing applied to electronic health records for identifying patients with non-alcoholic fatty liver disease at risk for disease progression.
Link: https://doi.org/S1386-5056(19)30269-2 Authors: Van Vleck, Tielman T; Chan, Lili; Coca, Steven G; Craven, Catherine K; Do, Ron; Ellis, Stephen B; Kannry, Joseph L; Loos, Ruth J F; Bonis, Peter A; Cho, Judy; Nadkarni, Girish N Abstract: Electronic health record (EHR) systems contain structured data (such as diagnostic codes) and unstructured data (clinical documentation). Clinical insights…
Read MoreMachine Learning in Glomerular Diseases: Promise for Precision Medicine.
Link: https://doi.org/S0272-6386(19)30714-0 Authors: Nadkarni, Girish N; Chaudhary, Kumardeep; Coca, Steven G Abstract:
Read MoreA catalog of genetic loci associated with kidney function from analyses of a million individuals.
Link: https://doi.org/10.1038/s41588-019-0407-x Authors: Wuttke, Matthias; Li, Yong; Li, Man; Sieber, Karsten B; Feitosa, Mary F; Gorski, Mathias; Tin, Adrienne; Wang, Lihua; Chu, Audrey Y; Hoppmann, Anselm; Kirsten, Holger; Giri, Ayush; Chai, Jin-Fang; Sveinbjornsson, Gardar; Tayo, Bamidele O; Nutile, Teresa; Fuchsberger, Christian; Marten, Jonathan; Cocca, Massimiliano; Ghasemi, Sahar; Xu, Yizhe; Horn, Katrin; Noce, Damia; van der…
Read MoreGenetics of Chronic Kidney Disease Stages Across Ancestries: The PAGE Study.
Link: https://doi.org/10.3389/fgene.2019.00494 Authors: Lin, Bridget M; Nadkarni, Girish N; Tao, Ran; Graff, Mariaelisa; Fornage, Myriam; Buyske, Steven; Matise, Tara C; Highland, Heather M; Wilkens, Lynne R; Carlson, Christopher S; Park, S Lani; Setiawan, V Wendy; Ambite, Jose Luis; Heiss, Gerardo; Boerwinkle, Eric; Lin, Dan-Yu; Morris, Andrew P; Loos, Ruth J F; Kooperberg, Charles; North, Kari…
Read MoreApolipoprotein L1, Cardiovascular Disease and Hypertension: More Questions than Answers.
Link: https://doi.org/S0733-8651(19)30035-9 Authors: Patel, Niralee; Nadkarni, Girish N Abstract: Ethnic disparities in health outcomes exist among multiple complex diseases especially cardiovascular disease, hypertension, and kidney disease. Recent discoveries in genetics have taught us that these disparities go beyond environmental and socioeconomic factors. The discovery of ethnic-specific risk variants in the Apolipoprotein L1 (APOL1) gene on…
Read MoreAdiposity and risk of decline in glomerular filtration rate: meta-analysis of individual participant data in a global consortium.
Link: https://doi.org/10.1136/bmj.k5301 Authors: Chang, Alex R; Grams, Morgan E; Ballew, Shoshana H; Bilo, Henk; Correa, Adolfo; Evans, Marie; Gutierrez, Orlando M; Hosseinpanah, Farhad; Iseki, Kunitoshi; Kenealy, Timothy; Klein, Barbara; Kronenberg, Florian; Lee, Brian J; Li, Yuanying; Miura, Katsuyuki; Navaneethan, Sankar D; Roderick, Paul J; Valdivielso, Jose M; Visseren, Frank L J; Zhang, Luxia; Gansevoort, Ron…
Read MoreChange in albuminuria and subsequent risk of end-stage kidney disease: an individual participant-level consortium meta-analysis of observational studies.
Link: https://doi.org/S2213-8587(18)30313-9 Authors: Coresh, Josef; Heerspink, Hiddo J L; Sang, Yingying; Matsushita, Kunihiro; Arnlov, Johan; Astor, Brad C; Black, Corri; Brunskill, Nigel J; Carrero, Juan-Jesus; Feldman, Harold I; Fox, Caroline S; Inker, Lesley A; Ishani, Areef; Ito, Sadayoshi; Jassal, Simerjot; Konta, Tsuneo; Polkinghorne, Kevan; Romundstad, Solfrid; Solbu, Marit D; Stempniewicz, Nikita; Stengel, Benedicte; Tonelli, Marcello;…
Read MoreTrans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies.
Link: https://doi.org/10.1038/s41467-018-07867-7 Authors: Morris, Andrew P; Le, Thu H; Wu, Haojia; Akbarov, Artur; van der Most, Peter J; Hemani, Gibran; Smith, George Davey; Mahajan, Anubha; Gaulton, Kyle J; Nadkarni, Girish N; Valladares-Salgado, Adan; Wacher-Rodarte, Niels; Mychaleckyj, Josyf C; Dueker, Nicole D; Guo, Xiuqing; Hai, Yang; Haessler, Jeffrey; Kamatani, Yoichiro; Stilp, Adrienne M; Zhu, Gu; Cook,…
Read More