Association of SARS-CoV-2 viral load at admission with in-hospital acute kidney injury: A retrospective cohort study.

By Amir Safavi | February 24, 2021 |

Link: https://doi.org/10.1371/journal.pone.0247366 Authors: Paranjpe, Ishan; Chaudhary, Kumardeep; Johnson, Kipp W; Jaladanki, Suraj K; Zhao, Shan; De Freitas, Jessica K; Pujdas, Elisabet; Chaudhry, Fayzan; Bottinger, Erwin P; Levin, Matthew A; Fayad, Zahi A; Charney, Alexander W; Houldsworth, Jane; Cordon-Cardo, Carlos; Glicksberg, Benjamin S; Nadkarni, Girish N Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the…

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Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline.

By Amir Safavi | October 31, 2020 |

Link: https://doi.org/S0085-2538(20)31239-4 Authors: Gorski, Mathias; Jung, Bettina; Li, Yong; Matias-Garcia, Pamela R; Wuttke, Matthias; Coassin, Stefan; Thio, Chris H L; Kleber, Marcus E; Winkler, Thomas W; Wanner, Veronika; Chai, Jin-Fang; Chu, Audrey Y; Cocca, Massimiliano; Feitosa, Mary F; Ghasemi, Sahar; Hoppmann, Anselm; Horn, Katrin; Li, Man; Nutile, Teresa; Scholz, Markus; Sieber, Karsten B; Teumer, Alexander;…

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Outcomes of Patients on Maintenance Dialysis Hospitalized with COVID-19.

By Amir Safavi | October 30, 2020 |

Link: https://doi.org/10.2215/CJN.12360720 Authors: Chan, Lili; Jaladanki, Suraj K; Somani, Sulaiman; Paranjpe, Ishan; Kumar, Arvind; Zhao, Shan; Kaufman, Lewis; Leisman, Staci; Sharma, Shuchita; He, John Cijiang; Murphy, Barbara; Fayad, Zahi A; Levin, Matthew A; Bottinger, Erwin P; Charney, Alexander W; Glicksberg, Benjamin S; Coca, Steven G; Nadkarni, Girish N; , Abstract:

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SGLT2 Inhibitors: Emerging Roles in the Protection Against Cardiovascular and Kidney Disease Among Diabetic Patients.

By Amir Safavi | October 28, 2020 |

Link: https://doi.org/10.2147/IJNRD.S268811 Authors: Vasquez-Rios, George; Nadkarni, Girish N Abstract: Type 2 diabetes mellitus (T2DM) is a prevalent disease with the severe clinical implications including myocardial infarction, stroke, and kidney disease. Therapies focusing on glycemic control in T2DM such as biguanides, sulfonylureas, thiazolidinediones, and insulin-based regimens have largely failed to substantially improve cardiovascular and kidney outcomes.…

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Incorporating kidney disease measures into cardiovascular risk prediction: Development and validation in 9 million adults from 72 datasets.

By Amir Safavi | October 14, 2020 |

Link: https://doi.org/10.1016/j.eclinm.2020.100552 Authors: Matsushita, Kunihiro; Jassal, Simerjot K; Sang, Yingying; Ballew, Shoshana H; Grams, Morgan E; Surapaneni, Aditya; Arnlov, Johan; Bansal, Nisha; Bozic, Milica; Brenner, Hermann; Brunskill, Nigel J; Chang, Alex R; Chinnadurai, Rajkumar; Cirillo, Massimo; Correa, Adolfo; Ebert, Natalie; Eckardt, Kai-Uwe; Gansevoort, Ron T; Gutierrez, Orlando; Hadaegh, Farzad; He, Jiang; Hwang, Shih-Jen; Jafar, Tazeen…

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Utilization of Deep Learning for Subphenotype Identification in Sepsis-Associated Acute Kidney Injury.

By Amir Safavi | October 8, 2020 |

Link: https://doi.org/10.2215/CJN.09330819 Authors: Chaudhary, Kumardeep; Vaid, Akhil; Duffy, Áine; Paranjpe, Ishan; Jaladanki, Suraj; Paranjpe, Manish; Johnson, Kipp; Gokhale, Avantee; Pattharanitima, Pattharawin; Chauhan, Kinsuk; O’Hagan, Ross; Van Vleck, Tielman; Coca, Steven G; Cooper, Richard; Glicksberg, Benjamin; Bottinger, Erwin P; Chan, Lili; Nadkarni, Girish N Abstract: Sepsis-associated AKI is a heterogeneous clinical entity. We aimed to agnostically…

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Characteristics and Outcomes of Individuals With Pre-existing Kidney Disease and COVID-19 Admitted to Intensive Care Units in the United States.

By Amir Safavi | September 19, 2020 |

Link: https://doi.org/S0272-6386(20)30999-9 Authors: Flythe, Jennifer E; Assimon, Magdalene M; Tugman, Matthew J; Chang, Emily H; Gupta, Shruti; Shah, Jatan; Sosa, Marie Anne; Renaghan, Amanda DeMauro; Melamed, Michal L; Wilson, F Perry; Neyra, Javier A; Rashidi, Arash; Boyle, Suzanne M; Anand, Shuchi; Christov, Marta; Thomas, Leslie F; Edmonston, Daniel; Leaf, David E; , Abstract: Underlying kidney…

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The association of standard Kt/V and surface area-normalized standard Kt/V with clinical outcomes in hemodialysis patients.

By Amir Safavi | August 18, 2020 |

Link: https://doi.org/10.1111/hdi.12865 Authors: Pattharanitima, Pattharawin; Chauhan, Kinsuk; El Shamy, Osama; Chaudhary, Kumardeep; Sharma, Shuchita; Coca, Steven G; Nadkarni, Girish N; Uribarri, Jaime; Chan, Lili Abstract: A previous study demonstrated that the surface area-normalized standard Kt/V (SAstdKt/V) was better associated with mortality than standard Kt/V (stdKt/V). This study investigates the association of SAstdKt/V and stdKt/V with…

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