Utilizing large language models in breast cancer management: systematic review.

By Amir Safavi | March 19, 2024 |

Link: https://doi.org/10.1007/s00432-024-05678-6 Authors: Sorin, Vera; Glicksberg, Benjamin S; Artsi, Yaara; Barash, Yiftach; Konen, Eli; Nadkarni, Girish N; Klang, Eyal Abstract: Despite advanced technologies in breast cancer management, challenges remain in efficiently interpreting vast clinical data for patient-specific insights. We reviewed the literature on how large language models (LLMs) such as ChatGPT might offer solutions in…

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Per- and polyfluoroalkyl substances (PFAS) exposure and thyroid cancer risk.

By Amir Safavi | October 24, 2023 |

Link: https://doi.org/10.1016/j.ebiom.2023.104831 Authors: van Gerwen, Maaike; Colicino, Elena; Guan, Haibin; Dolios, Georgia; Nadkarni, Girish N; Vermeulen, Roel C H; Wolff, Mary S; Arora, Manish; Genden, Eric M; Petrick, Lauren M Abstract: Although per- and polyfluoroalkyl substances (PFAS) exposure is a potential contributor to the increasing thyroid cancer trend, limited studies have investigated the association between…

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Genetic hallmarks of recurrent/metastatic adenoid cystic carcinoma.

By Amir Safavi | March 5, 2023 |

Link: https://doi.org/128227 Authors: Ho, Allen S; Ochoa, Angelica; Jayakumaran, Gowtham; Zehir, Ahmet; Valero Mayor, Cristina; Tepe, Justin; Makarov, Vladimir; Dalin, Martin G; He, Jie; Bailey, Mark; Montesion, Meagan; Ross, Jeffrey S; Miller, Vincent A; Chan, Lindsay; Ganly, Ian; Dogan, Snjezana; Katabi, Nora; Tsipouras, Petros; Ha, Patrick; Agrawal, Nishant; Solit, David B; Futreal, P Andrew; El…

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Human WDR5 promotes breast cancer growth and metastasis via KMT2-independent translation regulation.

By Amir Safavi | August 31, 2022 |

Link: https://doi.org/10.7554/eLife.78163 Authors: Cai, Wesley L; Chen, Jocelyn Fang-Yi; Chen, Huacui; Wingrove, Emily; Kurley, Sarah J; Chan, Lok Hei; Zhang, Meiling; Arnal-Estape, Anna; Zhao, Minghui; Balabaki, Amer; Li, Wenxue; Yu, Xufen; Krop, Ethan D; Dou, Yali; Liu, Yansheng; Jin, Jian; Westbrook, Thomas F; Nguyen, Don X; Yan, Qin Abstract: Metastatic breast cancer remains a major…

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Deciphering intratumoral heterogeneity using integrated clonal tracking and single-cell transcriptome analyses.

By Amir Safavi | November 11, 2021 |

Link: https://doi.org/10.1038/s41467-021-26771-1 Authors: Contreras-Trujillo, Humberto; Eerdeng, Jiya; Akre, Samir; Jiang, Du; Contreras, Jorge; Gala, Basia; Vergel-Rodriguez, Mary C; Lee, Yeachan; Jorapur, Aparna; Andreasian, Areen; Harton, Lisa; Bramlett, Charles S; Nogalska, Anna; Xiao, Gang; Lee, Jae-Woong; Chan, Lai N; Müschen, Markus; Merchant, Akil A; Lu, Rong Abstract: Cellular heterogeneity is a major cause of treatment resistance…

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