Rheumatoid Arthritis, Cognitive Impairment, and Neuroimaging Biomarkers: Results from the Mayo Clinic Study of Aging.

Link: https://doi.org/10.3233/JAD-220368 Authors: Vassilaki, Maria; Crowson, Cynthia S; Davis Iii, John M; Duong, Stephanie Q; Jones, David T; Nguyen, Aivi; Mielke, Michelle M; Vemuri, Prashanthi; Myasoedova, Elena Abstract: Observational studies suggested that dementia risk in patients with rheumatoid arthritis (RA) is higher than in the general population. To examine the associations of RA with cognitive…

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Type 2 Diabetes Partitioned Polygenic Scores Associate With Disease Outcomes in 454,193 Individuals Across 13 Cohorts.

Link: https://doi.org/10.2337/dc21-1395 Authors: DiCorpo, Daniel; LeClair, Jessica; Cole, Joanne B; Sarnowski, Chloé; Ahmadizar, Fariba; Bielak, Lawrence F; Blokstra, Anneke; Bottinger, Erwin P; Chaker, Layal; Chen, Yii-Der I; Chen, Ye; de Vries, Paul S; Faquih, Tariq; Ghanbari, Mohsen; Gudmundsdottir, Valborg; Guo, Xiuqing; Hasbani, Natalie R; Ibi, Dorina; Ikram, M Arfan; Kavousi, Maryam; Leonard, Hampton L; Leong,…

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Development and Validation of Prediction Models of Adverse Kidney Outcomes in the Population With and Without Diabetes.

Link: https://doi.org/10.2337/dc22-0698 Authors: Grams, Morgan E; Brunskill, Nigel J; Ballew, Shoshana H; Sang, Yingying; Coresh, Josef; Matsushita, Kunihiro; Surapaneni, Aditya; Bell, Samira; Carrero, Juan J; Chodick, Gabriel; Evans, Marie; Heerspink, Hiddo J L; Inker, Lesley A; Iseki, Kunitoshi; Kalra, Philip A; Kirchner, H Lester; Lee, Brian J; Levin, Adeera; Major, Rupert W; Medcalf, James; Nadkarni,…

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Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations.

Link: https://doi.org/S0092-8674(20)30822-9 Authors: Chen, Ming-Huei; Raffield, Laura M; Mousas, Abdou; Sakaue, Saori; Huffman, Jennifer E; Moscati, Arden; Trivedi, Bhavi; Jiang, Tao; Akbari, Parsa; Vuckovic, Dragana; Bao, Erik L; Zhong, Xue; Manansala, Regina; Laplante, Véronique; Chen, Minhui; Lo, Ken Sin; Qian, Huijun; Lareau, Caleb A; Beaudoin, Mélissa; Hunt, Karen A; Akiyama, Masato; Bartz, Traci M; Ben-Shlomo,…

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The Polygenic and Monogenic Basis of Blood Traits and Diseases.

Link: https://doi.org/S0092-8674(20)30999-5 Authors: Vuckovic, Dragana; Bao, Erik L; Akbari, Parsa; Lareau, Caleb A; Mousas, Abdou; Jiang, Tao; Chen, Ming-Huei; Raffield, Laura M; Tardaguila, Manuel; Huffman, Jennifer E; Ritchie, Scott C; Megy, Karyn; Ponstingl, Hannes; Penkett, Christopher J; Albers, Patrick K; Wigdor, Emilie M; Sakaue, Saori; Moscati, Arden; Manansala, Regina; Lo, Ken Sin; Qian, Huijun; Akiyama,…

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Metabolite Biomarkers of CKD Progression in Children.

Link: https://doi.org/10.2215/CJN.00220121 Authors: Denburg, Michelle R; Xu, Yunwen; Abraham, Alison G; Coresh, Josef; Chen, Jingsha; Grams, Morgan E; Feldman, Harold I; Kimmel, Paul L; Rebholz, Casey M; Rhee, Eugene P; Vasan, Ramachandran S; Warady, Bradley A; Furth, Susan L; , Abstract: Metabolomics facilitates the discovery of biomarkers and potential therapeutic targets for CKD progression. We…

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Continuous Kidney Replacement Therapy of the Future: Innovations in Information Technology, Data Analytics, and Quality Assurance Systems.

Link: https://doi.org/S1548-5595(21)00031-8 Authors: Neyra, Javier A; Nadkarni, Girish N Abstract: Continuous kidney replacement therapy is commonly used in the critically ill population. Despite the recent development in continuous kidney replacement therapy technology and clinical informatics, many aspects of continuous kidney replacement therapy delivery are still not fully standardized, and quality assurance programs for the provision…

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Natural Language Processing in Nephrology.

Link: https://doi.org/S1548-5595(22)00128-8 Authors: Van Vleck, Tielman T; Farrell, Douglas; Chan, Lili Abstract: Unstructured data in the electronic health records contain essential patient information. Natural language processing (NLP), teaching a computer to read, allows us to tap into these data without needing the time and effort of manual chart abstraction. The core first step for all…

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