Lumasiran, an RNAi Therapeutic for Primary Hyperoxaluria Type 1.

By Amir Safavi | March 5, 2023 |

Link: https://doi.org/10.1056/NEJMoa2021712 Authors: Garrelfs, Sander F; Frishberg, Yaacov; Hulton, Sally A; Koren, Michael J; O’Riordan, William D; Cochat, Pierre; Deschênes, Georges; Shasha-Lavsky, Hadas; Saland, Jeffrey M; Van’t Hoff, William G; Fuster, Daniel G; Magen, Daniella; Moochhala, Shabbir H; Schalk, Gesa; Simkova, Eva; Groothoff, Jaap W; Sas, David J; Meliambro, Kristin A; Lu, Jiandong; Sweetser, Marianne…

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Author Correction: Metabolic gatekeeper function of B-lymphoid transcription factors.

By Amir Safavi | March 5, 2023 |

Link: https://doi.org/10.1038/s41586-018-0164-5 Authors: Chan, Lai N; Chen, Zhengshan; Braas, Daniel; Lee, Jae-Woong; Xiao, Gang; Geng, Huimin; Cosgun, Kadriye Nehir; Hurtz, Christian; Shojaee, Seyedmehdi; Cazzaniga, Valeria; Schjerven, Hilde; Ernst, Thomas; Hochhaus, Andreas; Kornblau, Steven M; Konopleva, Marina; Pufall, Miles A; Cazzaniga, Giovanni; Liu, Grace J; Milne, Thomas A; Koeffler, H Phillip; Ross, Theodora S; Sánchez-García, Isidro;…

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Anticoagulation in Patients With COVID-19: JACC Review Topic of the Week.

By Amir Safavi | March 5, 2023 |

Link: https://doi.org/S0735-1097(22)00007-9 Authors: Farkouh, Michael E; Stone, Gregg W; Lala, Anuradha; Bagiella, Emilia; Moreno, Pedro R; Nadkarni, Girish N; Ben-Yehuda, Ori; Granada, Juan F; Dressler, Ovidiu; Tinuoye, Elizabeth O; Granada, Carlos; Bustamante, Jessica; Peyra, Carlos; Godoy, Lucas C; Palacios, Igor F; Fuster, Valentin Abstract: Clinical, laboratory, and autopsy findings support an association between coronavirus disease-2019…

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Neighborhood Childhood Opportunity, Race/Ethnicity, and Surgical Outcomes in Children With Congenital Heart Disease.

By Amir Safavi | March 5, 2023 |

Link: https://doi.org/S0735-1097(23)06037-0 Authors: Duong, Son Q; Elfituri, Mahmud O; Zaniletti, Isabella; Ressler, Robert W; Noelke, Clemens; Gelb, Bruce D; Pass, Robert H; Horowitz, Carol R; Seiden, Howard S; Anderson, Brett R Abstract: Racial and ethnic disparities in outcomes for children with congenital heart disease (CHD) coexist with disparities in educational, environmental, and economic opportunity. We…

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Cost-Effective Approach to the Laparoscopic Appendectomy : Balancing Disposable Instrument Cost With Operative Time.

By Amir Safavi | March 5, 2023 |

Link: https://doi.org/10.1177/0003134820923337 Authors: DeMare, Alexander M; Luehmann, Natalie C; Kawak, Samer; Abbott, Emily E; Long, Jordan; Akay, Begum; Brahmamdam, Pavan; Iacco, Anthony A; Novotny, Nathan M Abstract: Surgeons can help reduce health care spending by selecting affordable and efficient instruments. The laparoscopic appendectomy (LA) is commonly performed and can serve as a model for improving…

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Federated Learning in Health care Using Structured Medical Data.

By Amir Safavi | March 5, 2023 |

Link: https://doi.org/S2949-8139(22)00008-8 Authors: Oh, Wonsuk; Nadkarni, Girish N Abstract: The success of machine learning-based studies is largely subjected to accessing a large amount of data. However, accessing such data is typically not feasible within a single health system/hospital. Although multicenter studies are the most effective way to access a vast amount of data, sharing data…

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Multi-center retrospective cohort study applying deep learning to electrocardiograms to identify left heart valvular dysfunction.

By Amir Safavi | February 14, 2023 |

Link: https://doi.org/10.1038/s43856-023-00240-w Authors: Vaid, Akhil; Argulian, Edgar; Lerakis, Stamatios; Beaulieu-Jones, Brett K; Krittanawong, Chayakrit; Klang, Eyal; Lampert, Joshua; Reddy, Vivek Y; Narula, Jagat; Nadkarni, Girish N; Glicksberg, Benjamin S Abstract: Aortic Stenosis and Mitral Regurgitation are common valvular conditions representing a hidden burden of disease within the population. The aim of this study was to…

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