Posts by Amir Safavi
Development of a machine learning model using electrocardiogram signals to improve acute pulmonary embolism screening.
Link: https://doi.org/10.1093/ehjdh/ztab101 Authors: Somani, Sulaiman S; Honarvar, Hossein; Narula, Sukrit; Landi, Isotta; Lee, Shawn; Khachatoorian, Yeraz; Rehmani, Arsalan; Kim, Andrew; De Freitas, Jessica K; Teng, Shelly; Jaladanki, Suraj; Kumar, Arvind; Russak, Adam; Zhao, Shan P; Freeman, Robert; Levin, Matthew A; Nadkarni, Girish N; Kagen, Alexander C; Argulian, Edgar; Glicksberg, Benjamin S Abstract: Clinical scoring systems…
Read MoreArtificial Intelligence for AKI!Now: Let’s Not Await Plato’s Utopian Republic.
Link: https://doi.org/10.34067/KID.0003472021 Authors: Soranno, Danielle E; Bihorac, Azra; Goldstein, Stuart L; Kashani, Kianoush B; Menon, Shina; Nadkarni, Girish N; Neyra, Javier A; Pannu, Neesh I; Singh, Karandeep; Cerda, Jorge; Koyner, Jay L; , Abstract:
Read MoreDeciphering intratumoral heterogeneity using integrated clonal tracking and single-cell transcriptome analyses.
Link: https://doi.org/10.1038/s41467-021-26771-1 Authors: Contreras-Trujillo, Humberto; Eerdeng, Jiya; Akre, Samir; Jiang, Du; Contreras, Jorge; Gala, Basia; Vergel-Rodriguez, Mary C; Lee, Yeachan; Jorapur, Aparna; Andreasian, Areen; Harton, Lisa; Bramlett, Charles S; Nogalska, Anna; Xiao, Gang; Lee, Jae-Woong; Chan, Lai N; Müschen, Markus; Merchant, Akil A; Lu, Rong Abstract: Cellular heterogeneity is a major cause of treatment resistance…
Read MoreIdentification of discriminative gene-level and protein-level features associated with pathogenic gain-of-function and loss-of-function variants.
Link: https://doi.org/S0002-9297(21)00384-0 Authors: Sevim Bayrak, Cigdem; Stein, David; Jain, Aayushee; Chaudhary, Kumardeep; Nadkarni, Girish N; Van Vleck, Tielman T; Puel, Anne; Boisson-Dupuis, Stephanie; Okada, Satoshi; Stenson, Peter D; Cooper, David N; Schlessinger, Avner; Itan, Yuval Abstract: Identifying whether a given genetic mutation results in a gene product with increased (gain-of-function; GOF) or diminished (loss-of-function; LOF)…
Read MoreDerivation and Validation of Genome-Wide Polygenic Score for Ischemic Heart Failure.
Link: https://doi.org/10.1161/JAHA.121.021916 Authors: Paranjpe, Ishan; Tsao, Noah L; De Freitas, Jessica K; Judy, Renae; Chaudhary, Kumardeep; Forrest, Iain S; Jaladanki, Suraj K; Paranjpe, Manish; Sharma, Pranav; , ; , ; Glicksberg, Benjamin S; Narula, Jagat; Do, Ron; Damrauer, Scott M; Nadkarni, Girish N Abstract:
Read MoreContrastive learning improves critical event prediction in COVID-19 patients.
Link: https://doi.org/10.1016/j.patter.2021.100389 Authors: Wanyan, Tingyi; Honarvar, Hossein; Jaladanki, Suraj K; Zang, Chengxi; Naik, Nidhi; Somani, Sulaiman; De Freitas, Jessica K; Paranjpe, Ishan; Vaid, Akhil; Zhang, Jing; Miotto, Riccardo; Wang, Zhangyang; Nadkarni, Girish N; Zitnik, Marinka; Azad, Ariful; Wang, Fei; Ding, Ying; Glicksberg, Benjamin S Abstract: Deep learning (DL) models typically require large-scale, balanced training data…
Read MoreThe Association between Prevalence of Peritoneal Dialysis versus Hemodialysis and Patients’ Distance to Dialysis-Providing Facilities.
Link: https://doi.org/10.34067/KID.0004762021 Authors: Pattharanitima, Pattharawin; El Shamy, Osama; Chauhan, Kinsuk; Saha, Aparna; Wen, Huei Hsun; Sharma, Shuchita; Uribarri, Jaime; Chan, Lili Abstract: Accessibility to dialysis facilities plays a central role when deciding on a patient’s long-term dialysis modality. Studies investigating the effect of distance to nearest dialysis-providing unit on modality choice have yielded conflicting results.…
Read MoreUsing Deep-Learning Algorithms to Simultaneously Identify Right and Left Ventricular Dysfunction From the Electrocardiogram.
Link: https://doi.org/S1936-878X(21)00627-6 Authors: Vaid, Akhil; Johnson, Kipp W; Badgeley, Marcus A; Somani, Sulaiman S; Bicak, Mesude; Landi, Isotta; Russak, Adam; Zhao, Shan; Levin, Matthew A; Freeman, Robert S; Charney, Alexander W; Kukar, Atul; Kim, Bette; Danilov, Tatyana; Lerakis, Stamatios; Argulian, Edgar; Narula, Jagat; Nadkarni, Girish N; Glicksberg, Benjamin S Abstract: This study sought to develop…
Read MoreActivation of STAT3 signaling pathway in the kidney of COVID-19 patients.
Link: https://doi.org/10.1007/s40620-021-01173-0 Authors: Salem, Fadi; Li, Xue Zhu; Hindi, Judy; Casablanca, Nitzy Munoz; Zhong, Fang; El Jamal, Siraj M; Haroon Al Rasheed, Mohamed Rizwan; Li, Li; Lee, Kyung; Chan, Lili; He, John Cijiang Abstract: Acute kidney injury is common in patients with COVID-19, however mechanisms of kidney injury remain unclear. Since cytokine storm is likely…
Read MoreFactors Associated With Longitudinal Psychological and Physiological Stress in Health Care Workers During the COVID-19 Pandemic: Observational Study Using Apple Watch Data.
Link: https://doi.org/10.2196/31295 Authors: Hirten, Robert P; Danieletto, Matteo; Tomalin, Lewis; Choi, Katie Hyewon; Zweig, Micol; Golden, Eddye; Kaur, Sparshdeep; Helmus, Drew; Biello, Anthony; Pyzik, Renata; Calcagno, Claudia; Freeman, Robert; Sands, Bruce E; Charney, Dennis; Bottinger, Erwin P; Murrough, James W; Keefer, Laurie; Suarez-Farinas, Mayte; Nadkarni, Girish N; Fayad, Zahi A Abstract: The COVID-19 pandemic has…
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