Thrombosis, Bleeding, and the Observational Effect of Early Therapeutic Anticoagulation on Survival in Critically Ill Patients With COVID-19.

Link: https://doi.org/10.7326/M20-6739 Authors: Al-Samkari, Hanny; Gupta, Shruti; Leaf, Rebecca Karp; Wang, Wei; Rosovsky, Rachel P; Brenner, Samantha K; Hayek, Salim S; Berlin, Hanna; Kapoor, Rajat; Shaefi, Shahzad; Melamed, Michal L; Sutherland, Anne; Radbel, Jared; Green, Adam; Garibaldi, Brian T; Srivastava, Anand; Leonberg-Yoo, Amanda; Shehata, Alexandre M; Flythe, Jennifer E; Rashidi, Arash; Goyal, Nitender; Chan, Lili;…

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Contrastive Learning Improves Critical Event Prediction in COVID-19 Patients.

Link: https://doi.org/arXiv:2101.04013v1 Authors: Wanyan, Tingyi; Honarvar, Hossein; Jaladanki, Suraj K; Zang, Chengxi; Naik, Nidhi; Somani, Sulaiman; Freitas, Jessica K De; Paranjpe, Ishan; Vaid, Akhil; Miotto, Riccardo; Nadkarni, Girish N; Zitnik, Marinka; ArifulAzad, ; Wang, Fei; Ding, Ying; Glicksberg, Benjamin S Abstract: Machine Learning (ML) models typically require large-scale, balanced training data to be robust, generalizable,…

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Hyperglycemia is Associated With Increased Mortality in Critically Ill Patients With COVID-19.

Link: https://doi.org/S1530-891X(21)00005-7 Authors: Mazori, Alon Y; Bass, Ilana Ramer; Chan, Lili; Mathews, Kusum S; Altman, Deena R; Saha, Aparna; Soh, Howard; Wen, Huei Hsun; Bose, Sonali; Leven, Emily; Wang, Jing Gennie; Mosoyan, Gohar; Pattharanitima, Pattharawin; Greco, Giampaolo; Gallagher, Emily J Abstract: To explore the relationship between hyperglycemia in the presence and absence of diabetes mellitus…

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Increasing Prevalence of Frailty and Its Association with Readmission and Mortality Among Hospitalized Patients with IBD.

Link: https://doi.org/10.1007/s10620-020-06746-w Authors: Faye, Adam S; Wen, Timothy; Soroush, Ali; Ananthakrishnan, Ashwin N; Ungaro, Ryan; Lawlor, Garrett; Attenello, Frank J; Mack, William J; Colombel, Jean-Frederic; Lebwohl, Benjamin Abstract: Although age is often used as a clinical risk stratification tool, recent data have suggested that adverse outcomes are driven by frailty rather than chronological age. In…

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Sex differences in viral entry protein expression and host transcript responses to SARS-CoV-2.

Link: https://doi.org/rs.3.rs-100914 Authors: Sun, Mengying; Shankar, Rama; Ko, Meehyun; Chang, Christopher Daniel; Yeh, Shan-Ju; Li, Shilong; Liu, Ke; Zhou, Guoli; Xing, Jing; VanVelsen, Austin; VanVelsen, Tyler; Paithankar, Shreya; Feng, Benjamin Y; Young, Krista; Strug, Michael; Turco, Lauren; Wang, Zichen; Schadt, Eric; Chen, Rong; Li, Xiaohong; Oskotsky, Tomiko; Sirota, Marina; Glicksberg, Benjamin S; Nadkarni, Girish N;…

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Relational Learning Improves Prediction of Mortality in COVID-19 in the Intensive Care Unit.

Link: https://doi.org/10.1109/tbdata.2020.3048644 Authors: Wanyan, Tingyi; Vaid, Akhil; De Freitas, Jessica K; Somani, Sulaiman; Miotto, Riccardo; Nadkarni, Girish N; Azad, Ariful; Ding, Ying; Glicksberg, Benjamin S Abstract: Traditional Machine Learning (ML) models have had limited success in predicting Coronoavirus-19 (COVID-19) outcomes using Electronic Health Record (EHR) data partially due to not effectively capturing the inter-connectivity patterns…

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Retrospective cohort study of clinical characteristics of 2199 hospitalised patients with COVID-19 in New York City.

Link: https://doi.org/10.1136/bmjopen-2020-040736 Authors: Paranjpe, Ishan; Russak, Adam J; De Freitas, Jessica K; Lala, Anuradha; Miotto, Riccardo; Vaid, Akhil; Johnson, Kipp W; Danieletto, Matteo; Golden, Eddye; Meyer, Dara; Singh, Manbir; Somani, Sulaiman; Kapoor, Arjun; O’Hagan, Ross; Manna, Sayan; Nangia, Udit; Jaladanki, Suraj K; O’Reilly, Paul; Huckins, Laura M; Glowe, Patricia; Kia, Arash; Timsina, Prem; Freeman, Robert…

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