Intravenous alteplase for stroke with unknown time of onset guided by advanced imaging: systematic review and meta-analysis of individual patient data.

Link: https://doi.org/S0140-6736(20)32163-2 Authors: Thomalla, Götz; Boutitie, Florent; Ma, Henry; Koga, Masatoshi; Ringleb, Peter; Schwamm, Lee H; Wu, Ona; Bendszus, Martin; Bladin, Christopher F; Campbell, Bruce C V; Cheng, Bastian; Churilov, Leonid; Ebinger, Martin; Endres, Matthias; Fiebach, Jochen B; Fukuda-Doi, Mayumi; Inoue, Manabu; Kleinig, Timothy J; Latour, Lawrence L; Lemmens, Robin; Levi, Christopher R; Leys, Didier;…

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Machine Learning to Predict Mortality and Critical Events in a Cohort of Patients With COVID-19 in New York City: Model Development and Validation.

Link: https://doi.org/10.2196/24018 Authors: Vaid, Akhil; Somani, Sulaiman; Russak, Adam J; De Freitas, Jessica K; Chaudhry, Fayzan F; Paranjpe, Ishan; Johnson, Kipp W; Lee, Samuel J; Miotto, Riccardo; Richter, Felix; Zhao, Shan; Beckmann, Noam D; Naik, Nidhi; Kia, Arash; Timsina, Prem; Lala, Anuradha; Paranjpe, Manish; Golden, Eddye; Danieletto, Matteo; Singh, Manbir; Meyer, Dara; O’Reilly, Paul F;…

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Self-reported health without clinically measurable benefits among adult users of multivitamin and multimineral supplements: a cross-sectional study.

Link: https://doi.org/10.1136/bmjopen-2020-039119 Authors: Paranjpe, Manish D; Chin, Alfred C; Paranjpe, Ishan; Reid, Nicholas J; Duy, Phan Q; Wang, Jason K; O’Hagan, Ross; Arzani, Artine; Haghdel, Arsalan; Lim, Clarence C; Orhurhu, Vwaire; Urits, Ivan; Ngo, Anh L; Glicksberg, Benjamin S; Hall, Kathryn T; Mehta, Darshan; Cooper, Richard S; Nadkarni, Girish N Abstract: Multiple clinical trials fail…

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Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline.

Link: https://doi.org/S0085-2538(20)31239-4 Authors: Gorski, Mathias; Jung, Bettina; Li, Yong; Matias-Garcia, Pamela R; Wuttke, Matthias; Coassin, Stefan; Thio, Chris H L; Kleber, Marcus E; Winkler, Thomas W; Wanner, Veronika; Chai, Jin-Fang; Chu, Audrey Y; Cocca, Massimiliano; Feitosa, Mary F; Ghasemi, Sahar; Hoppmann, Anselm; Horn, Katrin; Li, Man; Nutile, Teresa; Scholz, Markus; Sieber, Karsten B; Teumer, Alexander;…

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Outcomes of Patients on Maintenance Dialysis Hospitalized with COVID-19.

Link: https://doi.org/10.2215/CJN.12360720 Authors: Chan, Lili; Jaladanki, Suraj K; Somani, Sulaiman; Paranjpe, Ishan; Kumar, Arvind; Zhao, Shan; Kaufman, Lewis; Leisman, Staci; Sharma, Shuchita; He, John Cijiang; Murphy, Barbara; Fayad, Zahi A; Levin, Matthew A; Bottinger, Erwin P; Charney, Alexander W; Glicksberg, Benjamin S; Coca, Steven G; Nadkarni, Girish N; , Abstract:

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SGLT2 Inhibitors: Emerging Roles in the Protection Against Cardiovascular and Kidney Disease Among Diabetic Patients.

Link: https://doi.org/10.2147/IJNRD.S268811 Authors: Vasquez-Rios, George; Nadkarni, Girish N Abstract: Type 2 diabetes mellitus (T2DM) is a prevalent disease with the severe clinical implications including myocardial infarction, stroke, and kidney disease. Therapies focusing on glycemic control in T2DM such as biguanides, sulfonylureas, thiazolidinediones, and insulin-based regimens have largely failed to substantially improve cardiovascular and kidney outcomes.…

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AKI Treated with Renal Replacement Therapy in Critically Ill Patients with COVID-19.

Link: https://doi.org/10.1681/ASN.2020060897 Authors: Gupta, Shruti; Coca, Steven G; Chan, Lili; Melamed, Michal L; Brenner, Samantha K; Hayek, Salim S; Sutherland, Anne; Puri, Sonika; Srivastava, Anand; Leonberg-Yoo, Amanda; Shehata, Alexandre M; Flythe, Jennifer E; Rashidi, Arash; Schenck, Edward J; Goyal, Nitender; Hedayati, S Susan; Dy, Rajany; Bansal, Anip; Athavale, Ambarish; Nguyen, H Bryant; Vijayan, Anitha; Charytan,…

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Incorporating kidney disease measures into cardiovascular risk prediction: Development and validation in 9 million adults from 72 datasets.

Link: https://doi.org/10.1016/j.eclinm.2020.100552 Authors: Matsushita, Kunihiro; Jassal, Simerjot K; Sang, Yingying; Ballew, Shoshana H; Grams, Morgan E; Surapaneni, Aditya; Arnlov, Johan; Bansal, Nisha; Bozic, Milica; Brenner, Hermann; Brunskill, Nigel J; Chang, Alex R; Chinnadurai, Rajkumar; Cirillo, Massimo; Correa, Adolfo; Ebert, Natalie; Eckardt, Kai-Uwe; Gansevoort, Ron T; Gutierrez, Orlando; Hadaegh, Farzad; He, Jiang; Hwang, Shih-Jen; Jafar, Tazeen…

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Utilization of Deep Learning for Subphenotype Identification in Sepsis-Associated Acute Kidney Injury.

Link: https://doi.org/10.2215/CJN.09330819 Authors: Chaudhary, Kumardeep; Vaid, Akhil; Duffy, Áine; Paranjpe, Ishan; Jaladanki, Suraj; Paranjpe, Manish; Johnson, Kipp; Gokhale, Avantee; Pattharanitima, Pattharawin; Chauhan, Kinsuk; O’Hagan, Ross; Van Vleck, Tielman; Coca, Steven G; Cooper, Richard; Glicksberg, Benjamin; Bottinger, Erwin P; Chan, Lili; Nadkarni, Girish N Abstract: Sepsis-associated AKI is a heterogeneous clinical entity. We aimed to agnostically…

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