Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies.

Link: https://doi.org/10.1038/s41467-018-07867-7 Authors: Morris, Andrew P; Le, Thu H; Wu, Haojia; Akbarov, Artur; van der Most, Peter J; Hemani, Gibran; Smith, George Davey; Mahajan, Anubha; Gaulton, Kyle J; Nadkarni, Girish N; Valladares-Salgado, Adan; Wacher-Rodarte, Niels; Mychaleckyj, Josyf C; Dueker, Nicole D; Guo, Xiuqing; Hai, Yang; Haessler, Jeffrey; Kamatani, Yoichiro; Stilp, Adrienne M; Zhu, Gu; Cook,…

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Fecal microbiota analysis of polycystic kidney disease patients according to renal function: A pilot study.

Link: https://doi.org/10.1177/1535370218818175 Authors: Yacoub, Rabi; Nadkarni, Girish N; McSkimming, Daniel I; Chaves, Lee D; Abyad, Sham; Bryniarski, Mark A; Honan, Amanda M; Thomas, Shruthi A; Gowda, Madan; He, John C; Uribarri, Jaime Abstract: The heterogeneity of the renal disease, therapeutic interventions, and the original cause of the renal failure, all directly affect the microbiota. We…

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Association of Central Venous Oxygen Saturation Variability and Mortality in Hemodialysis Patients.

Link: https://doi.org/10.1159/000494630 Authors: Zhang, Hanjie; Campos, Israel; Chan, Lili; Meyring-Wösten, Anna; Tapia Silva, Leticia M; Rivera Fuentes, Lemuel; Preciado, Priscila; Thijssen, Stephan; Kooman, Jeroen P; van der Sande, Frank M; Kotanko, Peter Abstract: Central venous oxygen saturation (ScvO2) is correlated with cardiac output. In most patients, ScvO2 declines during hemodialysis (HD) due to factors such…

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Increased mortality, morbidities, and costs after heart transplantation in heterotaxy syndrome and other complex situs arrangements.

Link: https://doi.org/S0022-5223(18)32970-2 Authors: Duong, Son Q; Godown, Justin; Soslow, Jonathan H; Thurm, Cary; Hall, Matt; Sainathan, Sandeep; Morell, Victor O; Dodd, Debra A; Feingold, Brian Abstract: Identify pediatric heart transplant (HT) recipients with heterotaxy and other complex arrangements of cardiac situs (heterotaxy/situs anomaly) and compare mortality, morbidities, length of stay (LOS), and costs to recipients…

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Kidney Biopsy-Related Complications in Hospitalized Patients with Acute Kidney Disease.

Link: https://doi.org/10.2215/CJN.04910418 Authors: Moledina, Dennis G; Luciano, Randy L; Kukova, Lidiya; Chan, Lili; Saha, Aparna; Nadkarni, Girish; Alfano, Sandra; Wilson, F Perry; Perazella, Mark A; Parikh, Chirag R Abstract: Patients are informed of the risk of kidney biopsy-related complications using data from nonhospitalized patients, which may underestimate the risk for hospitalized patients. We evaluated the…

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Relationship of Estimated GFR and Albuminuria to Concurrent Laboratory Abnormalities: An Individual Participant Data Meta-analysis in a Global Consortium.

Link: https://doi.org/S0272-6386(18)30916-8 Authors: Inker, Lesley A; Grams, Morgan E; Levey, Andrew S; Coresh, Josef; Cirillo, Massimo; Collins, John F; Gansevoort, Ron T; Gutierrez, Orlando M; Hamano, Takayuki; Heine, Gunnar H; Ishikawa, Shizukiyo; Jee, Sun Ha; Kronenberg, Florian; Landray, Martin J; Miura, Katsuyuki; Nadkarni, Girish N; Peralta, Carmen A; Rothenbacher, Dietrich; Schaeffner, Elke; Sedaghat, Sanaz; Shlipak,…

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Genome-wide association study of primary open-angle glaucoma in continental and admixed African populations.

Link: https://doi.org/10.1007/s00439-018-1943-7 Authors: Bonnemaijer, Pieter W M; Iglesias, Adriana I; Nadkarni, Girish N; Sanyiwa, Anna J; Hassan, Hassan G; Cook, Colin; , ; Simcoe, Mark; Taylor, Kent D; Schurmann, Claudia; Belbin, Gillian M; Kenny, Eimear E; Bottinger, Erwin P; van de Laar, Suzanne; Wiliams, Susan E I; Akafo, Stephen K; Ashaye, Adeyinka O; Zangwill, Linda…

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National Trends in Emergency Room Visits of Dialysis Patients for Adverse Drug Reactions.

Link: https://doi.org/10.1159/000489703 Authors: Chan, Lili; Saha, Aparna; Poojary, Priti; Chauhan, Kinsuk; Naik, Nidhi; Coca, Steven; Garimella, Pranav S; Nadkarni, Girish N Abstract: Various medications are cleared by the kidneys, therefore patients with impaired renal function, especially dialysis patients are at risk for adverse drug events (ADEs). There are limited studies on ADEs in maintenance dialysis…

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