Posts by Amir Safavi
Peripheral Transcriptomics in Acute and Long-Term Kidney Dysfunction in SARS-CoV2 Infection.
Link: https://doi.org/10.1101/2023.10.25.23297469 Authors: Jayaraman, Pushkala; Rajagopal, Madhumitha; Paranjpe, Ishan; Liharska, Lora; Suarez-Farinas, Mayte; Thompson, Ryan; Del Valle, Diane Marie; Beckmann, Noam; Oh, Wonsuk; Gulamali, Faris F; Kauffman, Justin; Gonzalez-Kozlova, Edgar; Dellepiane, Sergio; Vasquez-Rios, George; Vaid, Akhil; Jiang, Joy; Chen, Annie; Sakhuja, Ankit; Chen, Steven; Kenigsberg, Ephraim; He, John Cijiang; Coca, Steven G; Chan, Lili; Schadt,…
Read MorePer- and polyfluoroalkyl substances (PFAS) exposure and thyroid cancer risk.
Link: https://doi.org/10.1016/j.ebiom.2023.104831 Authors: van Gerwen, Maaike; Colicino, Elena; Guan, Haibin; Dolios, Georgia; Nadkarni, Girish N; Vermeulen, Roel C H; Wolff, Mary S; Arora, Manish; Genden, Eric M; Petrick, Lauren M Abstract: Although per- and polyfluoroalkyl substances (PFAS) exposure is a potential contributor to the increasing thyroid cancer trend, limited studies have investigated the association between…
Read MoreCirculating Metabolomic Associations with Neurocognitive Outcomes in Pediatric CKD.
Link: https://doi.org/10.2215/CJN.0000000000000318 Authors: Lee, Arthur M; Xu, Yunwen; Hooper, Stephen R; Abraham, Alison G; Hu, Jian; Xiao, Rui; Matheson, Matthew B; Brunson, Celina; Rhee, Eugene P; Coresh, Josef; Vasan, Ramachandran S; Schrauben, Sarah; Kimmel, Paul L; Warady, Bradley A; Furth, Susan L; Hartung, Erum A; Denburg, Michelle R; , Abstract: Children with CKD are at…
Read MoreDevelopment and Validation of a Formative Assessment Tool for Nephrology Fellows’ Clinical Reasoning.
Link: https://doi.org/10.2215/CJN.0000000000000315 Authors: Boyle, Suzanne M; Martindale, James; Parsons, Andrew S; Sozio, Stephen M; Hilburg, Rachel; Bahrainwala, Jehan; Chan, Lili; Stern, Lauren D; Warburton, Karen M Abstract: Diagnostic errors are commonly driven by failures in clinical reasoning. Deficits in clinical reasoning are common among graduate medical learners, including nephrology fellows. We created and validated an…
Read MoreA clustering approach to improve our understanding of the genetic and phenotypic complexity of chronic kidney disease.
Link: https://doi.org/10.21203/rs.3.rs-3424565/v1 Authors: Eoli, Andrea; Ibing, Susanne; Schurmann, Claudia; Nadkarni, Girish N; Heyne, Henrike; Böttinger, Erwin Abstract: Chronic kidney disease (CKD) is a complex disorder that causes a gradual loss of kidney function, affecting approximately 9.1% of the world’s population. Here, we use a soft-clustering algorithm to deconstruct its genetic heterogeneity. First, we selected 322…
Read MoreA clustering approach to improve our understanding of the genetic and phenotypic complexity of chronic kidney disease.
Link: https://doi.org/10.1101/2023.10.12.23296926 Authors: Eoli, A; Ibing, S; Schurmann, C; Nadkarni, G N; Heyne, H O; Böttinger, E Abstract: Chronic kidney disease (CKD) is a complex disorder that causes a gradual loss of kidney function, affecting approximately 9.1% of the world’s population. Here, we use a soft-clustering algorithm to deconstruct its genetic heterogeneity. First, we selected…
Read MoreImplications of the Use of Artificial Intelligence Predictive Models in Health Care Settings : A Simulation Study.
Link: https://doi.org/10.7326/M23-0949 Authors: Vaid, Akhil; Sawant, Ashwin; Suarez-Farinas, Mayte; Lee, Juhee; Kaul, Sanjeev; Kovatch, Patricia; Freeman, Robert; Jiang, Joy; Jayaraman, Pushkala; Fayad, Zahi; Argulian, Edgar; Lerakis, Stamatios; Charney, Alexander W; Wang, Fei; Levin, Matthew; Glicksberg, Benjamin; Narula, Jagat; Hofer, Ira; Singh, Karandeep; Nadkarni, Girish N Abstract: Substantial effort has been directed toward demonstrating uses of…
Read MoreComparing ChatGPT and GPT-4 performance in USMLE soft skill assessments.
Link: https://doi.org/10.1038/s41598-023-43436-9 Authors: Brin, Dana; Sorin, Vera; Vaid, Akhil; Soroush, Ali; Glicksberg, Benjamin S; Charney, Alexander W; Nadkarni, Girish; Klang, Eyal Abstract: The United States Medical Licensing Examination (USMLE) has been a subject of performance study for artificial intelligence (AI) models. However, their performance on questions involving USMLE soft skills remains unexplored. This study aimed…
Read MoreClinical Informatics in Critical Care Medicine.
Link: https://doi.org/10.59249/WTTU3055 Authors: Nadkarni, Girish N; Sakhuja, Ankit Abstract: Continuous monitoring and treatment of patients in intensive care units generates vast amounts of data. Critical Care Medicine clinicians incorporate this continuously evolving data to make split-second, life or death decisions for management of these patients. Despite the abundance of data, it can be challenging to…
Read MoreAssociation of Racial Residential Segregation With Long-Term Outcomes and Readmissions After Out-of-Hospital Cardiac Arrest Among Medicare Beneficiaries.
Link: https://doi.org/10.1161/JAHA.123.030138 Authors: Abbott, Ethan E; Buckler, David G; Hsu, Jesse Y; Abella, Benjamin S; Richardson, Lynne D; Carr, Brendan G; Zebrowski, Alexis M Abstract: Background The national impact of racial residential segregation on out-of-hospital cardiac arrest outcomes after initial resuscitation remains poorly understood. We sought to characterize the association between measures of racial and…
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