4research
Albuminuria Testing in Hypertension and Diabetes: An Individual-Participant Data Meta-Analysis in a Global Consortium.
Link: https://doi.org/10.1161/HYPERTENSIONAHA.121.17323 Authors: Shin, Jung-Im; Chang, Alex R; Grams, Morgan E; Coresh, Josef; Ballew, Shoshana H; Surapaneni, Aditya; Matsushita, Kunihiro; Bilo, Henk J G; Carrero, Juan J; Chodick, Gabriel; Daratha, Kenn B; Jassal, Simerjot K; Nadkarni, Girish N; Nelson, Robert G; Nowak, Christoph; Stempniewicz, Nikita; Sumida, Keiichi; Traynor, Jamie P; Woodward, Mark; Sang, Yingying; Gansevoort,…
Read MoreObesity, inflammatory and thrombotic markers, and major clinical outcomes in critically ill patients with COVID-19 in the US.
Link: https://doi.org/10.1002/oby.23245 Authors: Friedman, Allon N; Guirguis, John; Kapoor, Rajat; Gupta, Shruti; Leaf, David E; Timsina, Lava R; , Abstract: This study aimed to determine whether obesity is independently associated with major adverse clinical outcomes and inflammatory and thrombotic markers in critically ill patients with COVID-19. The primary outcome was in-hospital mortality in adults with…
Read MoreAcute Kidney Injury in Patients Hospitalized With COVID-19 in New York City: Temporal Trends From March 2020 to April 2021.
Link: https://doi.org/10.1016/j.xkme.2021.06.008 Authors: Dellepiane, Sergio; Vaid, Akhil; Jaladanki, Suraj K; Coca, Steven; Fayad, Zahi A; Charney, Alexander W; Bottinger, Erwin P; He, John Cijiang; Glicksberg, Benjamin S; Chan, Lili; Nadkarni, Girish Abstract:
Read MorePerformance of crisis standards of care guidelines in a cohort of critically ill COVID-19 patients in the United States.
Link: https://doi.org/10.1016/j.xcrm.2021.100376 Authors: Jezmir, Julia L; Bharadwaj, Maheetha; Chaitoff, Alexander; Diephuis, Bradford; Crowley, Conor P; Kishore, Sandeep P; Goralnick, Eric; Merriam, Louis T; Milliken, Aimee; Rhee, Chanu; Sadovnikoff, Nicholas; Shah, Sejal B; Gupta, Shruti; Leaf, David E; Feldman, William B; Kim, Edy Y; , Abstract: Many US states published crisis standards of care (CSC) guidelines…
Read MoreRare Coding Variants Associated With Electrocardiographic Intervals Identify Monogenic Arrhythmia Susceptibility Genes: A Multi-Ancestry Analysis.
Link: https://doi.org/10.1161/CIRCGEN.120.003300 Authors: Choi, Seung Hoan; Jurgens, Sean J; Haggerty, Christopher M; Hall, Amelia W; Halford, Jennifer L; Morrill, Valerie N; Weng, Lu-Chen; Lagerman, Braxton; Mirshahi, Tooraj; Pettinger, Mary; Guo, Xiuqing; Lin, Henry J; Alonso, Alvaro; Soliman, Elsayed Z; Kornej, Jelena; Lin, Honghuang; Moscati, Arden; Nadkarni, Girish N; Brody, Jennifer A; Wiggins, Kerri L; Cade,…
Read MoreDevelopment of a federated learning approach to predict acute kidney injury in adult hospitalized patients with COVID-19 in New York City.
Link: https://doi.org/10.1101/2021.07.25.21261105 Authors: Jaladanki, Suraj K; Vaid, Akhil; Sawant, Ashwin S; Xu, Jie; Shah, Kush; Dellepiane, Sergio; Paranjpe, Ishan; Chan, Lili; Kovatch, Patricia; Charney, Alexander W; Wang, Fei; Glicksberg, Benjamin S; Singh, Karandeep; Nadkarni, Girish N Abstract: Federated learning is a technique for training predictive models without sharing patient-level data, thus maintaining data security while…
Read MoreMapping the human genetic architecture of COVID-19.
Link: https://doi.org/10.1038/s41586-021-03767-x Authors: , Abstract:
Read MoreNon-invasive ventilation versus mechanical ventilation in hypoxemic patients with COVID-19.
Link: https://doi.org/10.1007/s15010-021-01633-6 Authors: Forrest, Iain S; Jaladanki, Suraj K; Paranjpe, Ishan; Glicksberg, Benjamin S; Nadkarni, Girish N; Do, Ron Abstract: Limited mechanical ventilators (MV) during the Coronavirus disease (COVID-19) pandemic have led to the use of non-invasive ventilation (NIV) in hypoxemic patients, which has not been studied well. We aimed to assess the association of…
Read MoreThe trans-ancestral genomic architecture of glycemic traits.
Link: https://doi.org/10.1038/s41588-021-00852-9 Authors: Chen, Ji; Spracklen, Cassandra N; Marenne, Gaëlle; Varshney, Arushi; Corbin, Laura J; Luan, Jian’an; Willems, Sara M; Wu, Ying; Zhang, Xiaoshuai; Horikoshi, Momoko; Boutin, Thibaud S; Mägi, Reedik; Waage, Johannes; Li-Gao, Ruifang; Chan, Kei Hang Katie; Yao, Jie; Anasanti, Mila D; Chu, Audrey Y; Claringbould, Annique; Heikkinen, Jani; Hong, Jaeyoung; Hottenga, Jouke-Jan;…
Read MoreGenetic pleiotropy of ERCC6 loss-of-function and deleterious missense variants links retinal dystrophy, arrhythmia, and immunodeficiency in diverse ancestries.
Link: https://doi.org/10.1002/humu.24220 Authors: Forrest, Iain S; Chaudhary, Kumardeep; Vy, Ha My T; Bafna, Shantanu; Kim, Soyeon; Won, Hong-Hee; Loos, Ruth J F; Cho, Judy; Pasquale, Louis R; Nadkarni, Girish N; Rocheleau, Ghislain; Do, Ron Abstract:
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