4research
Contrastive learning improves critical event prediction in COVID-19 patients.
Link: https://doi.org/10.1016/j.patter.2021.100389 Authors: Wanyan, Tingyi; Honarvar, Hossein; Jaladanki, Suraj K; Zang, Chengxi; Naik, Nidhi; Somani, Sulaiman; De Freitas, Jessica K; Paranjpe, Ishan; Vaid, Akhil; Zhang, Jing; Miotto, Riccardo; Wang, Zhangyang; Nadkarni, Girish N; Zitnik, Marinka; Azad, Ariful; Wang, Fei; Ding, Ying; Glicksberg, Benjamin S Abstract: Deep learning (DL) models typically require large-scale, balanced training data…
Read MoreThe Association between Prevalence of Peritoneal Dialysis versus Hemodialysis and Patients’ Distance to Dialysis-Providing Facilities.
Link: https://doi.org/10.34067/KID.0004762021 Authors: Pattharanitima, Pattharawin; El Shamy, Osama; Chauhan, Kinsuk; Saha, Aparna; Wen, Huei Hsun; Sharma, Shuchita; Uribarri, Jaime; Chan, Lili Abstract: Accessibility to dialysis facilities plays a central role when deciding on a patient’s long-term dialysis modality. Studies investigating the effect of distance to nearest dialysis-providing unit on modality choice have yielded conflicting results.…
Read MoreUsing Deep-Learning Algorithms to Simultaneously Identify Right and Left Ventricular Dysfunction From the Electrocardiogram.
Link: https://doi.org/S1936-878X(21)00627-6 Authors: Vaid, Akhil; Johnson, Kipp W; Badgeley, Marcus A; Somani, Sulaiman S; Bicak, Mesude; Landi, Isotta; Russak, Adam; Zhao, Shan; Levin, Matthew A; Freeman, Robert S; Charney, Alexander W; Kukar, Atul; Kim, Bette; Danilov, Tatyana; Lerakis, Stamatios; Argulian, Edgar; Narula, Jagat; Nadkarni, Girish N; Glicksberg, Benjamin S Abstract: This study sought to develop…
Read MoreActivation of STAT3 signaling pathway in the kidney of COVID-19 patients.
Link: https://doi.org/10.1007/s40620-021-01173-0 Authors: Salem, Fadi; Li, Xue Zhu; Hindi, Judy; Casablanca, Nitzy Munoz; Zhong, Fang; El Jamal, Siraj M; Haroon Al Rasheed, Mohamed Rizwan; Li, Li; Lee, Kyung; Chan, Lili; He, John Cijiang Abstract: Acute kidney injury is common in patients with COVID-19, however mechanisms of kidney injury remain unclear. Since cytokine storm is likely…
Read MoreFactors Associated With Longitudinal Psychological and Physiological Stress in Health Care Workers During the COVID-19 Pandemic: Observational Study Using Apple Watch Data.
Link: https://doi.org/10.2196/31295 Authors: Hirten, Robert P; Danieletto, Matteo; Tomalin, Lewis; Choi, Katie Hyewon; Zweig, Micol; Golden, Eddye; Kaur, Sparshdeep; Helmus, Drew; Biello, Anthony; Pyzik, Renata; Calcagno, Claudia; Freeman, Robert; Sands, Bruce E; Charney, Dennis; Bottinger, Erwin P; Murrough, James W; Keefer, Laurie; Suarez-Farinas, Mayte; Nadkarni, Girish N; Fayad, Zahi A Abstract: The COVID-19 pandemic has…
Read MorePrognostic value of polygenic risk scores for adults with psychosis.
Link: https://doi.org/10.1038/s41591-021-01475-7 Authors: Landi, Isotta; Kaji, Deepak A; Cotter, Liam; Van Vleck, Tielman; Belbin, Gillian; Preuss, Michael; Loos, Ruth J F; Kenny, Eimear; Glicksberg, Benjamin S; Beckmann, Noam D; O’Reilly, Paul; Schadt, Eric E; Achtyes, Eric D; Buckley, Peter F; Lehrer, Douglas; Malaspina, Dolores P; McCarroll, Steven A; Rapaport, Mark H; Fanous, Ayman H; Pato,…
Read MorePhe2vec: Automated disease phenotyping based on unsupervised embeddings from electronic health records.
Link: https://doi.org/10.1016/j.patter.2021.100337 Authors: De Freitas, Jessica K; Johnson, Kipp W; Golden, Eddye; Nadkarni, Girish N; Dudley, Joel T; Bottinger, Erwin P; Glicksberg, Benjamin S; Miotto, Riccardo Abstract: Robust phenotyping of patients from electronic health records (EHRs) at scale is a challenge in clinical informatics. Here, we introduce Phe2vec, an automated framework for disease phenotyping from…
Read MoreMachine Learning Prediction of Death in Critically Ill Patients With Coronavirus Disease 2019.
Link: https://doi.org/10.1097/CCE.0000000000000515 Authors: Churpek, Matthew M; Gupta, Shruti; Spicer, Alexandra B; Hayek, Salim S; Srivastava, Anand; Chan, Lili; Melamed, Michal L; Brenner, Samantha K; Radbel, Jared; Madhani-Lovely, Farah; Bhatraju, Pavan K; Bansal, Anip; Green, Adam; Goyal, Nitender; Shaefi, Shahzad; Parikh, Chirag R; Semler, Matthew W; Leaf, David E; , Abstract: Critically ill patients with coronavirus…
Read MoreDevelopment and validation of techniques for phenotyping ST-elevation myocardial infarction encounters from electronic health records.
Link: https://doi.org/10.1093/jamiaopen/ooab068 Authors: Somani, Sulaiman; Yoffie, Stephen; Teng, Shelly; Havaldar, Shreyas; Nadkarni, Girish N; Zhao, Shan; Glicksberg, Benjamin S Abstract: Classifying hospital admissions into various acute myocardial infarction phenotypes in electronic health records (EHRs) is a challenging task with strong research implications that remains unsolved. To our knowledge, this study is the first study to…
Read MoreDownregulation of exhausted cytotoxic T cells in gene expression networks of multisystem inflammatory syndrome in children.
Link: https://doi.org/10.1038/s41467-021-24981-1 Authors: Beckmann, Noam D; Comella, Phillip H; Cheng, Esther; Lepow, Lauren; Beckmann, Aviva G; Tyler, Scott R; Mouskas, Konstantinos; Simons, Nicole W; Hoffman, Gabriel E; Francoeur, Nancy J; Del Valle, Diane Marie; Kang, Gurpawan; Do, Anh; Moya, Emily; Wilkins, Lillian; Le Berichel, Jessica; Chang, Christie; Marvin, Robert; Calorossi, Sharlene; Lansky, Alona; Walker, Laura;…
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