Sleep in the Natural Environment: A Pilot Study.

Link: https://doi.org/10.3390/s20051378 Authors: Chaudhry, Fayzan F; Danieletto, Matteo; Golden, Eddye; Scelza, Jerome; Botwin, Greg; Shervey, Mark; De Freitas, Jessica K; Paranjpe, Ishan; Nadkarni, Girish N; Miotto, Riccardo; Glowe, Patricia; Stock, Greg; Percha, Bethany; Zimmerman, Noah; Dudley, Joel T; Glicksberg, Benjamin S Abstract:

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Global, regional, and national burden of chronic kidney disease, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.

Link: https://doi.org/S0140-6736(20)30045-3 Authors: , Abstract: Health system planning requires careful assessment of chronic kidney disease (CKD) epidemiology, but data for morbidity and mortality of this disease are scarce or non-existent in many countries. We estimated the global, regional, and national burden of CKD, as well as the burden of cardiovascular disease and gout attributable to…

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Racial and Ethnic Disparities in Pregnancy-Related Acute Kidney Injury.

Link: https://doi.org/10.34067/KID.0000102019 Authors: Beers, Kelly; Wen, Huei Hsun; Saha, Aparna; Chauhan, Kinsuk; Dave, Mihir; Coca, Steven; Nadkarni, Girish; Chan, Lili Abstract: Pregnancy-related AKI (PR-AKI) is increasing in the United States. PR-AKI is associated with adverse maternal outcomes. Disparities in racial/ethnic differences in PR-AKI by race have not been studied. This was a retrospective cohort study…

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Polymer-based or Polymer-free Stents in Patients at High Bleeding Risk.

Link: https://doi.org/10.1056/NEJMoa1910021 Authors: Windecker, Stephan; Latib, Azeem; Kedhi, Elvin; Kirtane, Ajay J; Kandzari, David E; Mehran, Roxana; Price, Matthew J; Abizaid, Alexandre; Simon, Daniel I; Worthley, Stephen G; Zaman, Azfar; Hudec, Martin; Poliacikova, Petra; Abdul Ghapar, A Kahar Bin; Selvaraj, Kamaraj; Petrov, Ivo; Mylotte, Darren; Pinar, Eduardo; Moreno, Raul; Fabbiocchi, Franco; Pasupati, Sanjeevan; Kim, Hyo-Soo;…

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Human and mouse essentiality screens as a resource for disease gene discovery.

Link: https://doi.org/10.1038/s41467-020-14284-2 Authors: Cacheiro, Pilar; Muñoz-Fuentes, Violeta; Murray, Stephen A; Dickinson, Mary E; Bucan, Maja; Nutter, Lauryl M J; Peterson, Kevin A; Haselimashhadi, Hamed; Flenniken, Ann M; Morgan, Hugh; Westerberg, Henrik; Konopka, Tomasz; Hsu, Chih-Wei; Christiansen, Audrey; Lanza, Denise G; Beaudet, Arthur L; Heaney, Jason D; Fuchs, Helmut; Gailus-Durner, Valerie; Sorg, Tania; Prochazka, Jan; Novosadova,…

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The epichaperome is a mediator of toxic hippocampal stress and leads to protein connectivity-based dysfunction.

Link: https://doi.org/10.1038/s41467-019-14082-5 Authors: Inda, Maria Carmen; Joshi, Suhasini; Wang, Tai; Bolaender, Alexander; Gandu, Srinivasa; Koren Iii, John; Che, Alicia Yue; Taldone, Tony; Yan, Pengrong; Sun, Weilin; Uddin, Mohammad; Panchal, Palak; Riolo, Matthew; Shah, Smit; Barlas, Afsar; Xu, Ke; Chan, Lon Yin L; Gruzinova, Alexandra; Kishinevsky, Sarah; Studer, Lorenz; Fossati, Valentina; Noggle, Scott A; White, Julie…

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Natural language processing of electronic health records is superior to billing codes to identify symptom burden in hemodialysis patients.

Link: https://doi.org/S0085-2538(19)31116-0 Authors: Chan, Lili; Beers, Kelly; Yau, Amy A; Chauhan, Kinsuk; Duffy, Áine; Chaudhary, Kumardeep; Debnath, Neha; Saha, Aparna; Pattharanitima, Pattharawin; Cho, Judy; Kotanko, Peter; Federman, Alex; Coca, Steven G; Van Vleck, Tielman; Nadkarni, Girish N Abstract: Symptoms are common in patients on maintenance hemodialysis but identification is challenging. New informatics approaches including natural…

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Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels.

Link: https://doi.org/10.1038/s41588-019-0504-x Authors: Tin, Adrienne; Marten, Jonathan; Halperin Kuhns, Victoria L; Li, Yong; Wuttke, Matthias; Kirsten, Holger; Sieber, Karsten B; Qiu, Chengxiang; Gorski, Mathias; Yu, Zhi; Giri, Ayush; Sveinbjornsson, Gardar; Li, Man; Chu, Audrey Y; Hoppmann, Anselm; O’Connor, Luke J; Prins, Bram; Nutile, Teresa; Noce, Damia; Akiyama, Masato; Cocca, Massimiliano; Ghasemi, Sahar; van der Most,…

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