Trends and Racial Disparities of Palliative Care Use among Hospitalized Patients with ESKD on Dialysis.

Link: https://doi.org/10.1681/ASN.2018121256 Authors: Wen, Yumeng; Jiang, Changchuan; Koncicki, Holly M; Horowitz, Carol R; Cooper, Richard S; Saha, Aparna; Coca, Steven G; Nadkarni, Girish N; Chan, Lili Abstract: Study findings show that although palliative care decreases symptom burden, it is still underused in patients with ESKD. Little is known about disparity in use of palliative care…

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Comparison of Rotational with Orbital Atherectomy During Percutaneous Coronary Intervention for Coronary Artery Calcification: A Systematic Review and Meta-Analysis.

Link: https://doi.org/S1553-8389(19)30431-2 Authors: Sawant, Abhishek C; Panchal, Hemang; Radadiya, Dhruvil; Pomakov, Alexander; Tse, Gary; Liu, Tong; Sridhara, Srilekha; Rodriguez, Janelle; Prakash, Meghana Prakash Hiriyur; Kanwar, Nidhi; Kumar, Arnav; Banerjee, Kinjal; Wiesner, Philipp; Pershad, Ashish Abstract: Percutaneous coronary intervention (PCI) outcomes for patients with significant calcification have been consistently inferior compared to patients without significant calcification.…

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Augmented intelligence with natural language processing applied to electronic health records for identifying patients with non-alcoholic fatty liver disease at risk for disease progression.

Link: https://doi.org/S1386-5056(19)30269-2 Authors: Van Vleck, Tielman T; Chan, Lili; Coca, Steven G; Craven, Catherine K; Do, Ron; Ellis, Stephen B; Kannry, Joseph L; Loos, Ruth J F; Bonis, Peter A; Cho, Judy; Nadkarni, Girish N Abstract: Electronic health record (EHR) systems contain structured data (such as diagnostic codes) and unstructured data (clinical documentation). Clinical insights…

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A catalog of genetic loci associated with kidney function from analyses of a million individuals.

Link: https://doi.org/10.1038/s41588-019-0407-x Authors: Wuttke, Matthias; Li, Yong; Li, Man; Sieber, Karsten B; Feitosa, Mary F; Gorski, Mathias; Tin, Adrienne; Wang, Lihua; Chu, Audrey Y; Hoppmann, Anselm; Kirsten, Holger; Giri, Ayush; Chai, Jin-Fang; Sveinbjornsson, Gardar; Tayo, Bamidele O; Nutile, Teresa; Fuchsberger, Christian; Marten, Jonathan; Cocca, Massimiliano; Ghasemi, Sahar; Xu, Yizhe; Horn, Katrin; Noce, Damia; van der…

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Genetics of Chronic Kidney Disease Stages Across Ancestries: The PAGE Study.

Link: https://doi.org/10.3389/fgene.2019.00494 Authors: Lin, Bridget M; Nadkarni, Girish N; Tao, Ran; Graff, Mariaelisa; Fornage, Myriam; Buyske, Steven; Matise, Tara C; Highland, Heather M; Wilkens, Lynne R; Carlson, Christopher S; Park, S Lani; Setiawan, V Wendy; Ambite, Jose Luis; Heiss, Gerardo; Boerwinkle, Eric; Lin, Dan-Yu; Morris, Andrew P; Loos, Ruth J F; Kooperberg, Charles; North, Kari…

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Prediction of the 1-Year Risk of Incident Lung Cancer: Prospective Study Using Electronic Health Records from the State of Maine.

Link: https://doi.org/10.2196/13260 Authors: Wang, Xiaofang; Zhang, Yan; Hao, Shiying; Zheng, Le; Liao, Jiayu; Ye, Chengyin; Xia, Minjie; Wang, Oliver; Liu, Modi; Weng, Ching Ho; Duong, Son Q; Jin, Bo; Alfreds, Shaun T; Stearns, Frank; Kanov, Laura; Sylvester, Karl G; Widen, Eric; McElhinney, Doff B; Ling, Xuefeng B Abstract: Lung cancer is the leading cause of…

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Determinants of Depressive Symptoms at 1 Year Following ICU Discharge in Survivors of ≥ 7 Days of Mechanical Ventilation: Results From the RECOVER Program, a Secondary Analysis of a Prospective Multicenter Cohort Study.

Link: https://doi.org/S0012-3692(19)31046-3 Authors: Hamilton, Mika; Tomlinson, George; Chu, Leslie; Robles, Priscila; Matte, Andrea; Burns, Stacey; Thomas, Claire; Lamontagne, Francois; Adhikari, Neill K J; Ferguson, Niall; Friedrich, Jan O; Rudkowski, Jill C; Skrobik, Yoanna; Meggison, Hilary; Cameron, Jill; Herridge, Margaret; , ; , Abstract: Moderate to severe depressive symptoms occur in up to one-third of patients…

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Apolipoprotein L1, Cardiovascular Disease and Hypertension: More Questions than Answers.

Link: https://doi.org/S0733-8651(19)30035-9 Authors: Patel, Niralee; Nadkarni, Girish N Abstract: Ethnic disparities in health outcomes exist among multiple complex diseases especially cardiovascular disease, hypertension, and kidney disease. Recent discoveries in genetics have taught us that these disparities go beyond environmental and socioeconomic factors. The discovery of ethnic-specific risk variants in the Apolipoprotein L1 (APOL1) gene on…

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