A Multimodal Video-Based AI Biomarker for Aortic Stenosis Development and Progression.

Link: https://doi.org/10.1001/jamacardio.2024.0595 Authors: Oikonomou, Evangelos K; Holste, Gregory; Yuan, Neal; Coppi, Andreas; McNamara, Robert L; Haynes, Norrisa A; Vora, Amit N; Velazquez, Eric J; Li, Fan; Menon, Venu; Kapadia, Samir R; Gill, Thomas M; Nadkarni, Girish N; Krumholz, Harlan M; Wang, Zhangyang; Ouyang, David; Khera, Rohan Abstract: Aortic stenosis (AS) is a major public health…

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Integrated multiomics implicates dysregulation of ECM and cell adhesion pathways as drivers of severe COVID-associated kidney injury.

Link: https://doi.org/10.1101/2024.03.18.24304401 Authors: Anandakrishnan, Nanditha; Yi, Zhengzi; Sun, Zeguo; Liu, Tong; Haydak, Jonathan; Eddy, Sean; Jayaraman, Pushkala; DeFronzo, Stefanie; Saha, Aparna; Sun, Qian; Yang, Dai; Mendoza, Anthony; Mosoyan, Gohar; Wen, Huei Hsun; Schaub, Jennifer A; Fu, Jia; Kehrer, Thomas; Menon, Rajasree; Otto, Edgar A; Godfrey, Bradley; Suarez-Farinas, Mayte; Leffters, Sean; Twumasi, Akosua; Meliambro, Kristin; Charney,…

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Artificial intelligence-guided detection of under-recognized cardiomyopathies on point-of-care cardiac ultrasound.

Link: https://doi.org/10.1101/2024.03.10.24304044 Authors: Oikonomou, Evangelos K; Holste, Gregory; Coppi, Andreas; McNamara, Robert L; Nadkarni, Girish N; Baloescu, Cristiana; Krumholz, Harlan M; Wang, Zhangyang; Khera, Rohan Abstract: Point-of-care ultrasonography (POCUS) enables access to cardiac imaging directly at the bedside but is limited by brief acquisition, variation in acquisition quality, and lack of advanced protocols. To develop…

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A Multimodality Video-Based AI Biomarker For Aortic Stenosis Development And Progression.

Link: https://doi.org/10.1101/2023.09.28.23296234 Authors: Oikonomou, Evangelos K; Holste, Gregory; Yuan, Neal; Coppi, Andreas; McNamara, Robert L; Haynes, Norrisa; Vora, Amit N; Velazquez, Eric J; Li, Fan; Menon, Venu; Kapadia, Samir R; Gill, Thomas M; Nadkarni, Girish N; Krumholz, Harlan M; Wang, Zhangyang; Ouyang, David; Khera, Rohan Abstract: Aortic stenosis (AS) is a major public health challenge…

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Publication: Novel Intracranial Pressure Monitoring Using Non-Invasive Deep Learning Approach

A research study published as a preprint on February 27, 2024, by the AIMS Lab, showcases an innovative deep-learning approach that could redefine the field of intracranial pressure monitoring. In conditions like severe acute brain injuries (SABIs), including strokes and traumatic brain injuries, accurate measurement of intracranial pressure (ICP) can be significant for managing the…

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Publication: Deep Learning Insights on RV Function from ECG

In a groundbreaking study published on 29 December 2023 in the Journal of the American Heart Association, AIMS researchers have unveiled a novel approach to assess right ventricular (RV) size and function using deep learning-enabled electrocardiogram (ECG) analysis. Traditionally, assessing metrics like right ventricular ejection fraction (RVEF) and end-diastolic volume (RVEDV) required advanced imaging techniques,…

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Pediatric ECG-Based Deep Learning to Predict Left Ventricular Dysfunction and Remodeling.

Link: https://doi.org/10.1161/CIRCULATIONAHA.123.067750 Authors: Mayourian, Joshua; La Cava, William G; Vaid, Akhil; Nadkarni, Girish N; Ghelani, Sunil J; Mannix, Rebekah; Geva, Tal; Dionne, Audrey; Alexander, Mark E; Duong, Son Q; Triedman, John K Abstract: Artificial intelligence-enhanced ECG analysis shows promise to detect ventricular dysfunction and remodeling in adult populations. However, its application to pediatric populations remains…

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Derivation, External Validation and Clinical Implications of a deep learning approach for intracranial pressure estimation using non-cranial waveform measurements.

Link: https://doi.org/10.1101/2024.01.30.24301974 Authors: Gulamali, Faris; Jayaraman, Pushkala; Sawant, Ashwin S; Desman, Jacob; Fox, Benjamin; Chang, Annie; Soong, Brian Y; Arivazaghan, Naveen; Reynolds, Alexandra S; Duong, Son Q; Vaid, Akhil; Kovatch, Patricia; Freeman, Robert; Hofer, Ira S; Sakhuja, Ankit; Dangayach, Neha S; Reich, David S; Charney, Alexander W; Nadkarni, Girish N Abstract: Increased intracranial pressure (ICP)…

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Remote Monitoring and Artificial Intelligence: Outlook for 2050.

Link: https://doi.org/10.1213/ANE.0000000000006712 Authors: Feinstein, Max; Katz, Daniel; Demaria, Samuel; Hofer, Ira S Abstract: Remote monitoring and artificial intelligence will become common and intertwined in anesthesiology by 2050. In the intraoperative period, technology will lead to the development of integrated monitoring systems that will integrate multiple data streams and allow anesthesiologists to track patients more effectively.…

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Quantitative Prediction of Right Ventricular Size and Function From the ECG.

Link: https://doi.org/10.1161/JAHA.123.031671 Authors: Duong, Son Q; Vaid, Akhil; My, Vy Thi Ha; Butler, Liam R; Lampert, Joshua; Pass, Robert H; Charney, Alexander W; Narula, Jagat; Khera, Rohan; Sakhuja, Ankit; Greenspan, Hayit; Gelb, Bruce D; Do, Ron; Nadkarni, Girish N Abstract: Right ventricular ejection fraction (RVEF) and end-diastolic volume (RVEDV) are not readily assessed through traditional…

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