Posts Tagged ‘Nephrology’
Certain heterozygous variants in the kinase domain of the serine/threonine kinase NEK8 can cause an autosomal dominant form of polycystic kidney disease.
Link: https://doi.org/S0085-2538(23)00559-8 Authors: Claus, Laura R; Chen, Chuan; Stallworth, Jennifer; Turner, Joshua L; Slaats, Gisela G; Hawks, Alexandra L; Mabillard, Holly; Senum, Sarah R; Srikanth, Sujata; Flanagan-Steet, Heather; Louie, Raymond J; Silver, Josh; Lerner-Ellis, Jordan; Morel, Chantal; Mighton, Chloe; Sleutels, Frank; van Slegtenhorst, Marjon; van Ham, Tjakko; Brooks, Alice S; Dorresteijn, Eiske M; Barakat, Tahsin…
Read MoreDigital health and acute kidney injury: consensus report of the 27th Acute Disease Quality Initiative workgroup.
Link: https://doi.org/10.1038/s41581-023-00744-7 Authors: Kashani, Kianoush B; Awdishu, Linda; Bagshaw, Sean M; Barreto, Erin F; Claure-Del Granado, Rolando; Evans, Barbara J; Forni, Lui G; Ghosh, Erina; Goldstein, Stuart L; Kane-Gill, Sandra L; Koola, Jejo; Koyner, Jay L; Liu, Mei; Murugan, Raghavan; Nadkarni, Girish N; Neyra, Javier A; Ninan, Jacob; Ostermann, Marlies; Pannu, Neesh; Rashidi, Parisa; Ronco,…
Read MoreDeep Learning on Electrocardiograms for Prediction of In-hospital Intradialytic Hypotension in Patients with ESKD.
Link: https://doi.org/10.34067/KID.0000000000000208 Authors: Vaid, Akhil; Takkavatakarn, Kullaya; Divers, Jasmin; Charytan, David M; Chan, Lili; Nadkarni, Girish N Abstract: Intradialytic hypotension is common in patients who are on hemodialysis. We applied deep learning techniques to ECGs to predict patients at risk of IDH. The performance of the model was good with an AUC of 0.763 and…
Read MoreInteratrial Block Association With Adverse Cardiovascular Outcomes in Patients Without a History of Atrial Fibrillation.
Link: https://doi.org/S2405-500X(23)00254-2 Authors: Lampert, Joshua; Power, David; Havaldar, Shreyas; Govindarajulu, Usha; Kawamura, Iwanari; Maan, Abhishek; Miller, Marc A; Menon, Kartikeya; Koruth, Jacob; Whang, William; Bagiella, Emilia; Bayes-Genis, Antoni; Musikantow, Daniel; Turagam, Mohit; Bayes de Luna, Antoni; Halperin, Jonathan; Dukkipati, Srinivas R; Vaid, Akhil; Nadkarni, Girish; Glicksberg, Benjamin; Fuster, Valentin; Reddy, Vivek Y Abstract: Interatrial block…
Read MoreProteomic characterization of acute kidney injury in patients hospitalized with SARS-CoV2 infection.
Link: https://doi.org/10.1038/s43856-023-00307-8 Authors: Paranjpe, Ishan; Jayaraman, Pushkala; Su, Chen-Yang; Zhou, Sirui; Chen, Steven; Thompson, Ryan; Del Valle, Diane Marie; Kenigsberg, Ephraim; Zhao, Shan; Jaladanki, Suraj; Chaudhary, Kumardeep; Ascolillo, Steven; Vaid, Akhil; Gonzalez-Kozlova, Edgar; Kauffman, Justin; Kumar, Arvind; Paranjpe, Manish; Hagan, Ross O; Kamat, Samir; Gulamali, Faris F; Xie, Hui; Harris, Joceyln; Patel, Manishkumar; Argueta, Kimberly;…
Read MoreEvaluation of Plasma Biomarkers to Predict Major Adverse Kidney Events in Hospitalized Patients With COVID-19.
Link: https://doi.org/S0272-6386(23)00648-0 Authors: Menez, Steven; Coca, Steven G; Moledina, Dennis G; Wen, Yumeng; Chan, Lili; Thiessen-Philbrook, Heather; Obeid, Wassim; Garibaldi, Brian T; Azeloglu, Evren U; Ugwuowo, Ugochukwu; Sperati, C John; Arend, Lois J; Rosenberg, Avi Z; Kaushal, Madhurima; Jain, Sanjay; Wilson, F Perry; Parikh, Chirag R; , Abstract: Patients hospitalized with COVID-19 are at increased…
Read MoreJoint Modeling of Clinical and Biomarker Data in Acute Kidney Injury Defines Unique Subphenotypes with Differing Outcomes.
Link: https://doi.org/10.2215/CJN.0000000000000156 Authors: Vasquez-Rios, George; Oh, Wonsuk; Lee, Samuel; Bhatraju, Pavan; Mansour, Sherry G; Moledina, Dennis G; Gulamali, Faris F; Siew, Edward D; Garg, Amit X; Sarder, Pinaki; Chinchilli, Vernon M; Kaufman, James S; Hsu, Chi-Yuan; Liu, Kathleen D; Kimmel, Paul L; Go, Alan S; Wurfel, Mark M; Himmelfarb, Jonathan; Parikh, Chirag R; Coca, Steven…
Read MoreProteomic Characterization of Acute Kidney Injury in Patients Hospitalized with SARS-CoV2 Infection.
Link: https://doi.org/10.21203/rs.3.rs-2379226/v1 Authors: Nadkami, Girish; Paranjpe, Ishan; Jayaraman, Pushkala; Su, Chen-Yang; Zhou, Sirui; Chen, Steven; Valle, Diane Del; Thompson, Ryan; Kenigsberg, Ephraim; Zhao, Shan; Jaladanki, Suraj; Chaudhary, Kumardeep; Ascolillo, Steven; Vaid, Akhil; Gonzalez-Kozlova, Edgar; Kumar, Arvind; Paranjpe, Manish; O’Hagan, Ross; Kamat, Samir; Gulamali, Faris; Kauffman, Justin; Xie, Hui; Harris, Joceyln; Patel, Manishkumar; Argueta, Kimberly; Batchelor,…
Read MoreTrends of Acute Kidney Injury Requiring Dialysis Among Hospitalized Patients Undergoing Invasive Electrophysiology Procedures.
Link: https://doi.org/10.1097/HPC.0000000000000214 Authors: Wen, Yumeng; Hosseini Dehkordi, Seyed Hamed; Wei, Xin; Lucas, Claire Huang; Paranjpe, Ishan; Yan, Dexi; Gholitabar, Farid; Mehta, Davendra; Chan, Lili; Meisels, Ira Abstract: Electrophysiology (EP) procedures carry the risk of kidney injury due to contrast/hemodynamic fluctuations. We aim to evaluate the national epidemiology of acute kidney injury requiring dialysis (AKI-D) in…
Read MorePotential kidney toxicity from the antiviral drug tenofovir: new indications, new formulations, and a new prodrug.
Link: https://doi.org/10.1097/MNH.0000000000000392 Authors: Chan, Lili; Asriel, Benjamin; Eaton, Ellen F; Wyatt, Christina M Abstract: The antiviral agent tenofovir is highly effective for the treatment of HIV and hepatitis B virus infections, and the older prodrug tenofovir disoproxil fumarate (TDF) is also a component of daily preexposure prophylaxis (PrEP) to reduce the risk of HIV infection…
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