Applications of machine learning methods in kidney disease: hope or hype?

By Amir Safavi | March 5, 2023 |

Link: https://doi.org/10.1097/MNH.0000000000000604 Authors: Chan, Lili; Vaid, Akhil; Nadkarni, Girish N Abstract: The universal adoption of electronic health records, improvement in technology, and the availability of continuous monitoring has generated large quantities of healthcare data. Machine learning is increasingly adopted by nephrology researchers to analyze this data in order to improve the care of their patients.…

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Analysis of Biomarkers Within the Initial 2 Years Posttransplant and 5-Year Kidney Transplant Outcomes: Results From Clinical Trials in Organ Transplantation-17.

By Amir Safavi | March 5, 2023 |

Link: https://doi.org/10.1097/TP.0000000000002026 Authors: Faddoul, Geovani; Nadkarni, Girish N; Bridges, Nancy D; Goebel, Jens; Hricik, Donald E; Formica, Richard; Menon, Madhav C; Morrison, Yvonne; Murphy, Barbara; Newell, Kenneth; Nickerson, Peter; Poggio, Emilio D; Rush, David; Heeger, Peter S; , Abstract: An early posttransplant biomarker/surrogate marker for kidney allograft loss has the potential to guide targeted interventions.…

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APOL1 renal risk variants are associated with obesity and body composition in African ancestry adults: An observational genotype-phenotype association study.

By Amir Safavi | March 5, 2023 |

Link: https://doi.org/10.1097/MD.0000000000027785 Authors: Nadkarni, Girish N; Fei, Kezhen; Galarneau, Genevieve; Gao, Yan; Wilson, James G; Cooper, Richard; Madden, Ebony B; Denny, Joshua C; Richardson, Lynne D; Pollak, Martin; Loos, Ruth J F; Horowitz, Carol R Abstract: While increased obesity prevalence among persons of African ancestry (AAs) compared to persons of European ancestry (EAs) is linked…

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Serum potassium and adverse outcomes across the range of kidney function: a CKD Prognosis Consortium meta-analysis.

By Amir Safavi | March 5, 2023 |

Link: https://doi.org/10.1093/eurheartj/ehy100 Authors: Kovesdy, Csaba P; Matsushita, Kunihiro; Sang, Yingying; Brunskill, Nigel J; Carrero, Juan J; Chodick, Gabriel; Hasegawa, Takeshi; Heerspink, Hiddo L; Hirayama, Atsushi; Landman, Gijs W D; Levin, Adeera; Nitsch, Dorothea; Wheeler, David C; Coresh, Josef; Hallan, Stein I; Shalev, Varda; Grams, Morgan E; , Abstract: Both hypo- and hyperkalaemia can have immediate…

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Including measures of chronic kidney disease to improve cardiovascular risk prediction by SCORE2 and SCORE2-OP.

By Amir Safavi | March 5, 2023 |

Link: https://doi.org/10.1093/eurjpc/zwac176 Authors: Matsushita, Kunihiro; Kaptoge, Stephen; Hageman, Steven H J; Sang, Yingying; Ballew, Shoshana H; Grams, Morgan E; Surapaneni, Aditya; Sun, Luanluan; Arnlov, Johan; Bozic, Milica; Brenner, Hermann; Brunskill, Nigel J; Chang, Alex R; Chinnadurai, Rajkumar; Cirillo, Massimo; Correa, Adolfo; Ebert, Natalie; Eckardt, Kai-Uwe; Gansevoort, Ron T; Gutierrez, Orlando; Hadaegh, Farzad; He, Jiang; Hwang,…

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Association between intradialytic central venous oxygen saturation and ultrafiltration volume in chronic hemodialysis patients.

By Amir Safavi | March 5, 2023 |

Link: https://doi.org/10.1093/ndt/gfx271 Authors: Zhang, Hanjie; Chan, Lili; Meyring-Wösten, Anna; Campos, Israel; Preciado, Priscila; Kooman, Jeroen P; van der Sande, Frank M; Fuertinger, Doris; Thijssen, Stephan; Kotanko, Peter Abstract: Cardiac disease is highly prevalent in hemodialysis (HD) patients. Decreased tissue perfusion, including cardiac, due to high ultrafiltration volumes (UFVs) is considered to be one of the…

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Major cardiovascular events and subsequent risk of kidney failure with replacement therapy: a CKD Prognosis Consortium study.

By Amir Safavi | March 5, 2023 |

Link: https://doi.org/10.1093/eurheartj/ehac825 Authors: Mark, Patrick B; Carrero, Juan J; Matsushita, Kunihiro; Sang, Yingying; Ballew, Shoshana H; Grams, Morgan E; Coresh, Josef; Surapaneni, Aditya; Brunskill, Nigel J; Chalmers, John; Chan, Lili; Chang, Alex R; Chinnadurai, Rajkumar; Chodick, Gabriel; Cirillo, Massimo; de Zeeuw, Dick; Evans, Marie; Garg, Amit X; Gutierrez, Orlando M; Heerspink, Hiddo J L; Heine,…

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Estimated Glomerular Filtration Rate, Albuminuria, and Adverse Outcomes: An Individual-Participant Data Meta-Analysis.

By Amir Safavi | March 5, 2023 |

Link: https://doi.org/10.1001/jama.2023.17002 Authors: , ; Grams, Morgan E; Coresh, Josef; Matsushita, Kunihiro; Ballew, Shoshana H; Sang, Yingying; Surapaneni, Aditya; Alencar de Pinho, Natalia; Anderson, Amanda; Appel, Lawrence J; Ärnlöv, Johan; Azizi, Fereidoun; Bansal, Nisha; Bell, Samira; Bilo, Henk J G; Brunskill, Nigel J; Carrero, Juan J; Chadban, Steve; Chalmers, John; Chen, Jing; Ciemins, Elizabeth; Cirillo,…

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