Evaluation of the portability of computable phenotypes with natural language processing in the eMERGE network.

Link: https://doi.org/10.1038/s41598-023-27481-y Authors: Pacheco, Jennifer A; Rasmussen, Luke V; Wiley, Ken; Person, Thomas Nate; Cronkite, David J; Sohn, Sunghwan; Murphy, Shawn; Gundelach, Justin H; Gainer, Vivian; Castro, Victor M; Liu, Cong; Mentch, Frank; Lingren, Todd; Sundaresan, Agnes S; Eickelberg, Garrett; Willis, Valerie; Furmanchuk, Al’ona; Patel, Roshan; Carrell, David S; Deng, Yu; Walton, Nephi; Satterfield, Benjamin…

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The Kidney Failure Risk Equation: Evaluation of Novel Input Variables including eGFR Estimated Using the CKD-EPI 2021 Equation in 59 Cohorts.

Link: https://doi.org/10.1681/ASN.0000000000000050 Authors: Grams, Morgan E; Brunskill, Nigel J; Ballew, Shoshana H; Sang, Yingying; Coresh, Josef; Matsushita, Kunihiro; Surapaneni, Aditya; Bell, Samira; Carrero, Juan J; Chodick, Gabriel; Evans, Marie; Heerspink, Hiddo J L; Inker, Lesley A; Iseki, Kunitoshi; Kalra, Philip A; Kirchner, H Lester; Lee, Brian J; Levin, Adeera; Major, Rupert W; Medcalf, James; Nadkarni,…

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Normative Femoral and Tibial Lengths in a Modern Population of Twenty-First-Century U.S. Children.

Link: https://doi.org/10.2106/JBJS.22.00690 Authors: Chen, Chunho; Milbrandt, Todd A; Babadi, Elham; Duong, Stephanie Q; Larson, Dirk R; Shaughnessy, William J; Stans, Anthony A; Hull, Nathan C; Peterson, Hamlet A; Larson, A Noelle Abstract: The Green-Anderson (GA) leg-length data remain the gold standard for the age-based assessment of leg lengths in children despite their methodologic weaknesses. We…

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Machine learning-based marker for coronary artery disease: derivation and validation in two longitudinal cohorts.

Link: https://doi.org/S0140-6736(22)02079-7 Authors: Forrest, Iain S; Petrazzini, Ben O; Duffy, Áine; Park, Joshua K; Marquez-Luna, Carla; Jordan, Daniel M; Rocheleau, Ghislain; Cho, Judy H; Rosenson, Robert S; Narula, Jagat; Nadkarni, Girish N; Do, Ron Abstract: Binary diagnosis of coronary artery disease does not preserve the complexity of disease or quantify its severity or its associated…

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Autoencoders for sample size estimation for fully connected neural network classifiers.

Link: https://doi.org/10.1038/s41746-022-00728-0 Authors: Gulamali, Faris F; Sawant, Ashwin S; Kovatch, Patricia; Glicksberg, Benjamin; Charney, Alexander; Nadkarni, Girish N; Oermann, Eric Abstract: Sample size estimation is a crucial step in experimental design but is understudied in the context of deep learning. Currently, estimating the quantity of labeled data needed to train a classifier to a desired…

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Cannabis Use and CKD: Epidemiological Associations and Mendelian Randomization.

Link: https://doi.org/10.1016/j.xkme.2022.100582 Authors: Dellepiane, Sergio; Paranjpe, Ishan; Rajagopal, Madhumitha; Kamat, Samir; O’Hagan, Ross; Gulamali, Faris; Rein, Joshua L; Charney, Alexander W; Do, Ron; Coca, Steven; Glicksberg, Benjamin S; Nadkarni, Girish N Abstract: The association between cannabis use and chronic kidney disease (CKD) is controversial. We aimed to assess association of CKD with cannabis use in…

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Molecular states during acute COVID-19 reveal distinct etiologies of long-term sequelae.

Link: https://doi.org/10.1038/s41591-022-02107-4 Authors: Thompson, Ryan C; Simons, Nicole W; Wilkins, Lillian; Cheng, Esther; Del Valle, Diane Marie; Hoffman, Gabriel E; Cervia, Carlo; Fennessy, Brian; Mouskas, Konstantinos; Francoeur, Nancy J; Johnson, Jessica S; Lepow, Lauren; Le Berichel, Jessica; Chang, Christie; Beckmann, Aviva G; Wang, Ying-Chih; Nie, Kai; Zaki, Nicholas; Tuballes, Kevin; Barcessat, Vanessa; Cedillo, Mario A;…

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Artificial Intelligence and Machine Learning in Perioperative Acute Kidney Injury.

Link: https://doi.org/S2949-8139(22)00001-5 Authors: Takkavatakarn, Kullaya; Hofer, Ira S Abstract: Acute kidney injury (AKI) is a common complication after a surgery, especially in cardiac and aortic procedures, and has a significant impact on morbidity and mortality. Early identification of high-risk patients and providing effective prevention and therapeutic approach are the main strategies for reducing the possibility…

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